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Hepatic Mitochondrial Function in Sepsis

NCT00889083 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2020-07-31

No results posted yet for this study

Summary

Multi-organ failure due to sepsis is a major cause of death in critically ill patients. But the mechanisms leading to this condition are not fully understood. Mitochondrial dysfunction has been shown in skeletal muscle of critically ill septic patients. Liver is very important in sepsis as it is responsible of the synthesis of several inflammatory proteins. Moreover hepatic failure is associated to a bad outcome.

The aim of this study is to evaluate the hepatic mitochondrial function in sepsis.

Conditions

Sponsors & Collaborators

  • Professor C ICHAI

    lead OTHER

Principal Investigators

  • Carole Ichai, MD, PhD · Centre Hospitalier Universitaire de Nice

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-04-30
Primary Completion
2012-04-30
Completion
2012-04-30

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00889083 on ClinicalTrials.gov