3,4-Diaminopyridine Use in Lambert-Eaton Myasthenic Syndrome(LEMS) and Congenital Myasthenic Syndromes (CMS)
NCT00872950 · Status: APPROVED_FOR_MARKETING · Type: EXPANDED_ACCESS
Last updated 2022-04-11
Summary
The purpose of this study is to determine the effectiveness and adverse effects of 3,4-diaminopyridine for the treatment of the Lambert-Eaton Myasthenic Syndrome (LEMS) and Congenital Myasthenic Syndromes (CMS).
Conditions
- Lambert-Eaton Myasthenic Syndrome
- Congenital Myasthenic Syndrome
Interventions
- DRUG
-
3,4-DIAMINOPYRIDINE
Treatment will begin with a low dose and will be increased as clinically needed as tolerated. The upper limit will be a total of 100mg/day.
Sponsors & Collaborators
-
Lahey Clinic
lead OTHER
Principal Investigators
-
Jayashri Srinivasan, MD,MCRP,PhD · Lahey Clinic
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
Countries
- United States
Study Locations
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