Marathon, Genetics, Inflammation and the Cardiovascular System: MAGIC-Trial
NCT00845286 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 162
Last updated 2016-03-17
Summary
The purpose of the study is to determine the myocardial function and vascular adaptation after strenuous exercise in association with genotype/polymorphisms. We aim to investigate the effects of extreme endurance exercise on the cardiovascular system. Furthermore, the role of the inflammatory response and adaptive mechanisms of the vasculature are examined. Subclinical injuries to the myocardium and vascular wall are being investigated.
Conditions
Interventions
- BEHAVIORAL
-
Munich Marathon
42,195 km marathon run
Sponsors & Collaborators
-
Technical University of Munich
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 30 Years
- Max Age
- 60 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2008-09-30
- Primary Completion
- 2014-03-31
- Completion
- 2014-08-31
Countries
- Germany
Study Locations
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