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Automatic Tube Compensation (ATC) for Weaning Patients With Severe Neurotoxic Snake Envenoming

NCT00804011 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 41

Last updated 2008-12-08

No results posted yet for this study

Summary

In the mechanically ventilated patient, the single greatest cause of imposed work of breathing is the resistance caused by the endotracheal tube. Commonly used maneuvers to overcome this resistance include the use of continuous positive airway pressure or pressure support.However, a new mode of ventilatory support called automatic tube compensation (ATC) delivers exactly the amount of pressure necessary to overcome the resistive load imposed by the endotracheal tube for the flow measured at the time (so called variable pressure support).

The aim of this study is to evaluate whether a combination of pressure support with automatic tube compensation is superior to PS alone in weaning patients with severe neurotoxic snake envenoming.

Conditions

  • Snake Bite
  • Weaning
  • Mechanical Ventilation

Interventions

OTHER

ATC

Automatic tube compensation

OTHER

PSV

Pressure support ventilation

Sponsors & Collaborators

  • Dept of Pulmonary Medicine, PGIMER, Chandigarh

    collaborator UNKNOWN

  • Post Graduate Institute of Medical Education and Research, Chandigarh

    lead OTHER

Principal Investigators

  • Ritesh Agarwal, MD, DM, FCCP · PGIMER, INDIA

  • Ashutosh N Aggarwal, MD, DM, FCCP · PGIMER, INDIA

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-07-31
Primary Completion
2007-12-31
Completion
2008-04-30

Countries

  • India

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00804011 on ClinicalTrials.gov