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Acute Effects of Smoking on Airway Dendritic Cells

NCT00740896 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2009-04-08

No results posted yet for this study

Summary

Airway dendritic cells control pulmonary immune responses to inhaled particles. It is the aim of the present study to investigate the acute effects of smoking on the number and surface molecule expression of human airway dendritic cells.

Conditions

  • Tobacco Use Disorder

Interventions

BEHAVIORAL

Smoking

Active Comparator: Participants smoke 8 cigarettes in 4 hours.

BEHAVIORAL

Smoking

Sham Comparator: Participants are not allowed to smoke for 4 hours.

Sponsors & Collaborators

  • German Research Foundation

    collaborator OTHER

  • University of Rostock

    lead OTHER

Principal Investigators

  • Johann C. Virchow, Professor, MD, FRCP, FCCP · University of Rostock

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-06-30
Primary Completion
2008-11-30
Completion
2008-12-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00740896 on ClinicalTrials.gov