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Pharmacogenetic Determinants Of Treatment Response In Children

NCT00730678 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 8800

Last updated 2026-04-29

No results posted yet for this study

Summary

To investigate whether genetic polymorphisms in genes encoding proteins involved in the metabolism or effects of drugs or environmental agents influence the disposition or effects of these xenobiotic substrates. To investigate the nature of heritability and the genetic basis of pharmacogenetic traits by studying family members of individuals with specific genotypes.

Conditions

  • All Malignancies
  • Children Being Treated for Catastrophic Illness

Sponsors & Collaborators

Principal Investigators

  • Jun J Yang, Ph. D. · St. Jude Children's Research Hospital

  • Kristine Crews, PharmD, MSCI · St. Jude Children's Research Hospital

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1998-08-17
Primary Completion
2033-12-31
Completion
2034-03-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00730678 on ClinicalTrials.gov