Infrastructure for Developing Gastrointestinal Cancer Prognostic and Predictive Markers
NCT00716209 · Status: UNKNOWN · Type: OBSERVATIONAL
Last updated 2014-03-05
Summary
The proposal seeks to establish:
* A comprehensive compilation (database) of clinical information comprising clinical, histopathological, treatment and follow-up characteristics of past and future gastrointestinal cancer (GIC) cases in Singapore that can be shared by investigators. The characteristics will include clinical (eg age, sex, stage), histopathological (eg. grade, type), treatment (eg. treatment status, regimens) and outcome data (eg. survival, toxicity) from medical records.
* A collection (bank) of corresponding frozen and fixed tissue, blood and processed samples (enriched blood mononuclear cells, protein, RNA, DNA, tissue arrays) in Singapore that can be shared by the investigators.
* A gastrointestinal cancer co-operative group (GCCG) of clinicians and scientists researching prognostic and predictive markers in GIC, which will benefit from the multi-disciplinary knowledge, information and samples of its members.
* To characterise genetic polymorphisms related to Gastrointestinal cancer chemotherapy treatment in controls (healthy volunteers)
Conditions
Sponsors & Collaborators
-
Haematology-Oncology
lead OTHER
Principal Investigators
-
Ross Andrew Soo, MBBS · National University Hospital, Singapore
-
Alex Chang · Johns Hopkins Singapore International Medical Centre
-
Chung Yip Chan · Tan Tock Seng Hospital
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-09-30
- Primary Completion
- 2014-12-31
Countries
- Singapore
Study Locations
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