Effectiveness of a Community-level HIV/STD Prevention Intervention in Promoting Safer Sexual Behaviors in High-risk Populations

Summary

This study will evaluate the effectiveness of a community-level HIV prevention program in promoting safer sexual behaviors and reducing the transmission of HIV/sexually transmitted diseases among at-risk populations in China, India, Peru, Russia, and Zimbabwe.

Conditions

• HIV Infections
• Sexually Transmitted Diseases

Interventions

BEHAVIORAL

Community Popular Opinion Leader (C-POL)

The C-POL intervention will teach identified opinion leaders to share personalized HIV prevention messages in conversations with peers in an effort to change community norms. Opinion leaders will be taught skills for sharing HIV risk-reduction messages during four to five weekly training sessions. At least 15% of the community population will be trained as opinion leaders. After the initial training, opinion leaders will attend six to nine booster sessions over the next 2 years to reinforce and support continued conversation efforts.

BEHAVIORAL

HIV/STD educational materials

Communities will receive HIV/STD educational materials and treatment referral information to distribute to community members.

Sponsors & Collaborators

• National Institute of Mental Health (NIMH)

  collaborator NIH

• RTI International

  lead OTHER

Principal Investigators

• Carlos F. Caceres, PhD · Cayetano Heredia University, Lima, Peru

• David D. Celentano, ScD · The Johns Hopkins University, Baltimore, Maryland (India)

• Thomas J. Coates, PhD · University of California at Los Angeles, Los Angeles, California (Peru)

• Tyler D. Hartwell, PhD · RTI International, Research Triangle Park, North Carolina (DCC)

• Danuta Kasprzyk, PhD · Battelle Center for Public Health Research and Evaluation, Seattle, Washington (Zimbabwe)

• Jeffrey A. Kelly, PhD · Medical College of Wisconsin, Milwaukee, Wisconsin (Russia)

• Andrei P. Kozlov, PhD · Biomedical Center, St. Petersburg State University, St. Petersburg, Russia

• Willo Pequegnat, PhD · National Institute of Mental Health, Bethesda, Maryland

• Mary Jane Rotheram-Borus, PhD · University of California at Los Angeles, Los Angeles, California (China)

• Suniti Solomon, MD · YRG Centre for AIDS Research and Education, Chennai, India

• Godfrey B. Woelk, PhD · University of Zimbabwe Medical School, Harare, Zimbabwe

• Zunyou Wu, MD, PhD · Chinese Center for Disease Control and Prevention, Beijing, P.R. China

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

49 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2002-09-30

Primary Completion

2007-08-31

Completion

2007-08-31

Countries

• China
• India
• Peru
• Russia
• Zimbabwe

Study Locations