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Assessment of Circulating Copeptin Levels in Healthy Subjects and Patients With Renal Insufficiency After Oral Water Load and Hypertonic Saline Infusion

NCT00696605 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2017-02-27

No results posted yet for this study

Summary

The are 2 principal goals in this study:

1. To measure plasma copeptin levels in healthy subjects and to correlate them with plasma AVP concentrations and urine osmolalities in iso-, hypo-, and hyperosmolar states.
2. To measure plasma copeptin concentrations in patients with chronic renal failure under the same conditions described above, in order to characterize the impact of renal function on circulating copeptin levels in correlation to plasma AVP and urine osmolality.

Conditions

  • Hypoosmolality
  • Hyperosmolality
  • Renal Failure

Sponsors & Collaborators

  • Brahms AG

    collaborator INDUSTRY

  • Hospital Centre Biel/Bienne

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-07-31
Primary Completion
2009-01-31
Completion
2009-10-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00696605 on ClinicalTrials.gov