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Airway Dysfunction and Remodelling in Athletes Following Swimming Training in Chlorinated Pools

NCT00686452 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2008-12-22

No results posted yet for this study

Summary

Swimmers show the highest prevalence of asthma among elite athletes, certainly due to chlorine exposure. The consequences of a chronic exposure to chlorine compounds by swimmers and the mechanisms of asthme in this population are still poorly documented. Specific diagnostic criteria have been proposed by the International Olympic Committee - Medical Council (IOC-MC) and World anti-doping agency (WADA) to determine the presence of asthma in athletes. Using the more specific bronchial provocation tests, our aims are

1. to compare the prevalence of asthma in swimmers and control subjects
2. to analyze the Influence of chlorine exposure on bronchial inflammatory processes in swimmers versus control subjects
3. to study the time-course of changes in airway symptoms, responsiveness, inflammation and remodeling after cessation of training

Conditions

  • Asthma
  • Airway Hyperresponsiveness

Sponsors & Collaborators

  • Laval University

    lead OTHER

Eligibility

Min Age
14 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-03-31
Primary Completion
2009-05-31
Completion
2009-05-31

Countries

  • Canada

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00686452 on ClinicalTrials.gov