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Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT)

NCT00683696 · Status: TERMINATED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 1680

Last updated 2018-01-17

Study results available
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Summary

The EchoCRT trial evaluates the effects of Cardiac Resynchronization Therapy (CRT) on mortality and morbidity of subjects with heart failure due to left ventricular systolic dysfunction, already receiving optimized HF medication, with a narrow QRS width (\< 130 ms) and echocardiographic evidence of ventricular dyssynchrony.

Conditions

Interventions

DEVICE

Implantable Cardioverter Defibrillator with Cardiac Resynchronization Therapy (BIOTRONIK Lumax HF-T CRT-D)

All patients will receive a commercially available BIOTRONIK Lumax HF-T CRT-D system with ICD back-up enabled. Patients will be randomized to CRT=ON or CRT=OFF.

Sponsors & Collaborators

  • University of Zurich

    collaborator OTHER

  • Biotronik, Inc.

    lead INDUSTRY

Principal Investigators

  • Frank Ruschitzka, MD · University of Zurich, Switzerland

  • Johannes Holzmeister, MD · University of Zurich, Switzerland

  • William Abraham, MD · Principal Investigator (USA) at The Ohio State University, OH, USA

  • Jagmeet Singh, MD · Principal Investigator (USA) at Massachusetts General Hospital, MA, USA

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-08-31
Primary Completion
2013-03-31
Completion
2013-03-31

Countries

  • United States
  • Australia
  • Austria
  • Belgium
  • Canada
  • Czechia
  • Denmark
  • France
  • Germany
  • Israel
  • Italy
  • Netherlands
  • Poland
  • Portugal
  • Spain
  • Switzerland
  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00683696 on ClinicalTrials.gov