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Pre-Implantation Genetic Screening in Women Under the Age of 36 Years With Single Embryo Transfer

NCT00670059 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 240

Last updated 2008-05-01

No results posted yet for this study

Summary

BACKGROUND: Single-embryo transfer is a well-accepted strategy to avoid multiple pregnancies in an assisted reproductive technology programme. The selection of the embryo with the highest implantation potential is a crucial step. Besides the morphological quality and embryo kinetics up to the blastocyst stage, pre-implantation genetic screening (PGS) of aneuploidy has been advocated as an adjuvant approach by which to select the right embryo for transfer.

METHODS: Couples with a female partner younger than 36 years were randomly assigned to undergo transfer of a single blastocyst in a cycle with or without PGS using fluorescence in situ hybridization for the chromosomes X, Y, 13, 16, 18, 21 and 22.

Conditions

  • Live Birth Delivery Rate

Interventions

GENETIC

single embryo transfer without aneuploidy screening

without aneuploidy testing for the chromosomes XY, 13, 16, 18, 21, 22

GENETIC

single embryo transfer with aneuploidy screening

with aneuploidy testing for the chromosomes XY, 13, 16, 18, 21, 22

Sponsors & Collaborators

  • Vrije Universiteit Brussel

    lead OTHER

Study Design

Allocation
RANDOMIZED
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-10-31
Primary Completion
2007-06-30
Completion
2008-02-29

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00670059 on ClinicalTrials.gov