Effect of Prophylaxy of Amiodarone and Propranolol and Amiodarone With Propranolol in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft
NCT00654290 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 240
Last updated 2008-04-07
Summary
Atrial fibrillation is the most common arrhythmia post coronary bypass surgery, currently B-blockers are the class I indication to prevent AF post CABG. We decide to evaluate use of propranolol and amiodarone separately and together to find a better prophylaxis for AF peri-CABG
Conditions
Interventions
- DRUG
-
Amiodarone + Propranolol
Amiodarone and Propranolol 7 days pre-operation to 5 days post CABG
- DRUG
-
Amiodarone
Amiodarone treated 7 days pre-operation to 5 days post CABG
- DRUG
-
Propranolol
Propranolol from 7 days pre-operation to 5 days post CABG
Sponsors & Collaborators
-
Shiraz University of Medical Sciences
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 45 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-03-31
- Primary Completion
- 2008-01-31
- Completion
- 2008-02-29
Countries
- Iran
Study Locations
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