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Evaluation of the Role of Magnesium in Prevention of AF Post Cardiac Surgery

NCT06675500 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 130

Last updated 2025-08-17

Study results available
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Summary

Atrial fibrillation (AF) is a common complication after cardiac surgery. Most studies suggest that the frequency ranges between 25-40%.

Some studies have shown that serum hypomagnesaemia is common after coronary artery bypass grafts (CABG) and other types of cardiac surgery and is associated with postoperative morbidity such as atrial tachyarrhythmia.

The aim of the present study is to investigate the anti-arrhythmic effect of Magnesium Sulfate in prevention of atrial fibrillation post cardiac surgery.

Conditions

  • Atrial Fibrillation (AF)
  • Magnesium Sulfate
  • Post Cardiac Surgery Patients

Interventions

DRUG

Magnesium sulphate

Intravenous Magnesium sulphate followed by oral tablets of Magnesium sulphate

DRUG

Placebo

Intravenous infusion of Normal saline 0.9 followed by starch oral tablets

Sponsors & Collaborators

  • Ain Shams University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-11-01
Primary Completion
2025-04-15
Completion
2025-04-30

Countries

  • Egypt

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06675500 on ClinicalTrials.gov