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Measuring Neurological Impairment and Functional Visual Assessment In Spinocerebellar Ataxias

NCT00654251 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2009-04-29

No results posted yet for this study

Summary

Measuring the various difficulties patients with spinocerebellar ataxias (SCA) report in an accurate manner is important to be able to test any therapy that may be developed. As basic research identifies some therapy of this type, clinicians are planning studies that can either prove or disprove that such treatments actually have an effect. Walking problems and problems with eye movements that can give rise to visual complaints are common in the SCA's.

Existing neurological scales such as the "SARA" are based on the usual neurological examination items that can carry a degree of subjective bias. Also the intervals between numbers on such scores often do not carry the same "weight" so that the difference between a score of 1 and 2 may not be equal to difference between 2 and 3. Lastly, such scales done in the clinic setting capture only a brief period of a patient's day. We propose that examination of home based gait monitoring, timed tests of motor function and quantitative measures of visual problems in patients with SCA are more useful in measuring the disability in these patients.

Conditions

  • Spinocerebellar Ataxia

Sponsors & Collaborators

  • University of Texas

    collaborator OTHER

  • University of Mississippi Medical Center

    lead OTHER

Principal Investigators

  • James J Corbett, MD · University of Mississippi Medical Center

  • S H Subramony, MD · University of Texas

  • Sachin Kedar, MD · University of Mississippi Medical Center

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-02-29
Primary Completion
2009-02-28
Completion
2009-02-28

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00654251 on ClinicalTrials.gov