Comparing the Efficacy and Safety of Rosuvastatin With Atorvastatin and Simvastatin (SOLAR)
NCT00654173 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 4444
Last updated 2009-03-16
Summary
The purpose of this study is to compare the efficacy and safety of rosuvastatin with simvastatin and atorvastatin in reducing levels of low density lipoprotein cholesterol in subjects with hypercholesterolaemia
Conditions
Interventions
- DRUG
-
Rosuvastatin
- DRUG
-
Simvastatin
- DRUG
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Alex Gold, MD · AstraZeneca
-
Russell Esterline · AstraZeneca
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-06-30
- Completion
- 2004-09-30
More Related Trials
-
A Study to Determine the Number of Patients Who Reach Optimal Cholesterol Levels on Each of Three Different Treatments (0653A-121)
NCT00462748 ·Status: COMPLETED ·Phase: PHASE3
-
Registry On Efficacy and Safety Of Rosuvastatin, and Atorvastatin and Simvastatin In Hypercholesterolaemia
NCT01352897 ·Status: COMPLETED
-
Evaluation of the Efficacy and Safety of Rosuvastatin 5 mg Versus Pravastatin 40 mg and Atorvastatin 10 mg in Type IIa and IIb Hypercholesterolaemic Patients
NCT00631189 ·Status: COMPLETED ·Phase: PHASE4
-
PULSAR - A Prospective Study to Evaluate the Utility of Low Doses of the Statins Atorvastatin and Rosuvastatin.
NCT00329173 ·Status: COMPLETED ·Phase: PHASE3
-
Compare the Safety & Efficacy of Rosuvastatin 40mg in Combination With Ezetimibe 10mg
NCT00653445 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment of Hypercholesterolaemia in South Asian Subjects (IRIS)
NCT00654225 ·Status: COMPLETED ·Phase: PHASE3
-
Direct Statin Comparison of LDL-C Values: an Evaluation of Rosuvastatin Therapy
NCT00239330 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Investigate the Effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the Effect of Erythromycin on AZD5004 in Healthy Participants
NCT06948747 ·Status: COMPLETED ·Phase: PHASE1
-
Rosuvastatin Versus Atorvastatin in the Treatment of Hypercholesterolaemia in African American Subjects(ARIES)
NCT00653744 ·Status: COMPLETED ·Phase: PHASE3
-
48-wk Open Label Phase IIIb to Evaluate Efficacy and Safety
NCT00654602 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment of Hypercholesterolaemia in Hispanic Subjects (STARSHIP)
NCT00653965 ·Status: COMPLETED ·Phase: PHASE3
-
Polaris - Crestor 40 mg vs Atorvastatin 80 mg for 26 Weeks
NCT00653588 ·Status: COMPLETED ·Phase: PHASE3
-
IIIb 6 Week Open Label Multicentre Rosuvastatin & Simvastatin
NCT00654446 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of Crestor® (Rosuvastatin) in Daily Practice
NCT00837083 ·Status: COMPLETED
-
12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With Ezetimibe
NCT00525824 ·Status: COMPLETED ·Phase: PHASE3
-
Drug-drug Interaction Study of Rosuvastatin and AT-527 (R07496998)
NCT05154123 ·Status: COMPLETED ·Phase: PHASE1
-
Mercury II - Compare the Efficacy and Safety of Lipid Lowering Agents Atorvastatin and Simvastatin With Rosuvastatin in High Risk Subjects With Type IIa and IIb Hypercholesterolemia
NCT00654407 ·Status: COMPLETED ·Phase: PHASE3
-
COMETS - Compare the Efficacy of Rosuvastatin With Atorvastatin and Placebo in the Treatment of Non-Diabetic, Non-Atheroscleric, Metabolic Syndrome Subjects
NCT00654485 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of the Efficacy of Rosuvastatin in Daily Practice (TARGET)
NCT00396110 ·Status: COMPLETED
-
A Study of Ezetimibe Added On to Rosuvastatin Versus Up Titration of Rosuvastatin in Patients With Hypercholesterolemia (MK0653-139)
NCT00783263 ·Status: COMPLETED ·Phase: PHASE3
-
Ezetimibe/Simvastatin (MK-0653A) Versus Rosuvastatin Versus Doubling Statin Dose in Participants With Cardiovascular Disease and Diabetes Mellitus (MK-0653A-133)(COMPLETED)
NCT00862251 ·Status: COMPLETED ·Phase: PHASE3
-
Korean Rosuvastatin Effectiveness Study in Nondiabetic Metabolic Syndrome
NCT00335699 ·Status: COMPLETED ·Phase: PHASE4
-
Clinical Comparison of Low-dose Rosuvastatin Plus Ezetimibe Combination Therapy and High-dose Rosuvastatin Monotherapy in Patients With Minimal to Intermediate Coronary Artery Disease Without Percutaneous Coronary Intervention
NCT06186037 ·Status: RECRUITING ·Phase: PHASE4
-
A Study To Evaluate the Effect of Rosuvastatin On Intravascular Ultrasound-Derived Coronary Atheroma Burden (ASTEROID)
NCT00240318 ·Status: COMPLETED ·Phase: PHASE3
-
MK0653C in High Cardiovascular Risk Patients With High Cholesterol (Switch Study)(MK-0653C-162)
NCT01154036 ·Status: COMPLETED ·Phase: PHASE3