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The Effect of Nocturnal Haemodialysis on Arterial Stiffness

NCT00641875 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2015-04-27

No results posted yet for this study

Summary

Arterial stiffness refers to the accumulation of extracellular deposits of matrix and calcium which reduce blood vessel compliance. Although there is growing evidence that increased arterial stiffness is associated with chronic kidney disease (CKD), its pathogenesis is unclear. Pulse wave velocity (PWV) and augmentation index (AIx) provide tools for estimating arterial stiffness, and therefore predicting cardiovascular morbidity and mortality. The aims of the study are: (1) compare the effects of nocturnal and conventional haemodialysis on arterial stiffness, and (2) examine the relationship between arterial stiffness and clinical and biochemical parameters.

Conditions

Interventions

PROCEDURE

Nocturnal Hemodialysis

Sponsors & Collaborators

  • Melbourne Health

    lead OTHER

Principal Investigators

  • Michael Lian, FRACP, MBBS · Department of Nephrology, Melbourne Health

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-12-31
Primary Completion
2008-02-29
Completion
2008-02-29

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00641875 on ClinicalTrials.gov