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The Protective Effects Of Treatment With Hyperbaric Oxygen Prior To Bypass Heart Surgery

NCT00623142 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 81

Last updated 2019-07-15

No results posted yet for this study

Summary

The purpose of this study was to determine if treating patients who have coronary heart disease with hyperbaric oxygen (HBO) prior to coronary artery bypass graft (CABG) surgery reduces injury to the heart and vascular system during and after surgery. Furthermore, this study also aims to identify some of the post CABG clinical effects of HBO treatment prior to CABG.

Conditions

  • Myocardial Reperfusion Injury
  • Cytoprotection

Interventions

DRUG

Hyperbaric Oxygen

100% Oxygen at 2.4 ATA for 30 minutes followed by 5 minutes break followed by 100% Oxygen at 2.4 ATA for another 30 minutes. This intervention was given about 4 to 5 hours prior to CABG

Sponsors & Collaborators

  • North of England Medical & Hyperbaric Services

    collaborator UNKNOWN

  • Hull University Teaching Hospitals NHS Trust

    lead OTHER_GOV

Principal Investigators

  • Jeysen Z Yogaratnam, MB.BCh, BAO, MRCS · Hull & East Yorkshire NHS Trust (Castle Hill Hospital), United Kingdom

Study Design

Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-01-31
Primary Completion
2007-01-31
Completion
2008-01-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00623142 on ClinicalTrials.gov