Study of DNA Mutations in Predicting the Effect of External-Beam Radiation Therapy in Patients With Early Breast Cancer, Localized Prostate Cancer, or Gynecological Cancer
NCT00601406 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2200
Last updated 2013-08-26
Summary
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment.
PURPOSE: This clinical trial is evaluating DNA mutations in predicting the effect of external-beam radiation therapy in patients with early breast cancer, localized prostate cancer, or gynecologic cancer.
Conditions
- Breast Cancer
- Cervical Cancer
- Endometrial Cancer
- Fallopian Tube Cancer
- Ovarian Cancer
- Primary Peritoneal Cavity Cancer
- Prostate Cancer
- Sarcoma
- Vaginal Cancer
- Vulvar Cancer
Interventions
- GENETIC
-
gene expression analysis
- GENETIC
-
gene rearrangement analysis
- GENETIC
-
polymorphism analysis
- OTHER
-
laboratory biomarker analysis
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
The Christie NHS Foundation Trust
lead OTHER
Principal Investigators
-
Catherine West · The Christie NHS Foundation Trust
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-03-31
- Primary Completion
- 2008-02-29
Countries
- United Kingdom
Study Locations
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