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Molecular Genetic Basis of Invasive Breast Cancer Risk Associated With Lobular Carcinoma in Situ

NCT00581750 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 550

Last updated 2021-07-02

No results posted yet for this study

Summary

This study is being done in order to better understand the biology of an abnormal lesion found in breast tissue called "lobular carcinoma in situ" (LCIS). We are interested in studying LCIS. The LCIS is not a cancer itself, but is a marker for an increased risk of cancer. We would like to look for LCIS in breast tissue removed during surgery from patients with cancer or at high risk for cancer. If LCIS is found, we will search for genes that are expressed (turned on or off) differently than in normal breast tissue. The identification of such genes would help us better understand the biology of LCIS, and its possible relationship to breast cancer.

Conditions

Interventions

OTHER

Tissue specimen

Human tissues taken after the clinically indicated removal of these tissues from patients as part of their routine care.

Sponsors & Collaborators

Principal Investigators

  • Melissa Pilewskie, M.D. · Memorial Sloan Kettering Cancer Center

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2001-10-31
Primary Completion
2021-06-28
Completion
2021-06-28

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00581750 on ClinicalTrials.gov