Effects of Mixed Exercise Regime and L-Carnitine Supplementation in HIV Patients on HAART
NCT00572429 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL
Last updated 2012-12-19
Summary
HIV patients treated with Highly Active AntiRetroviral Therapy (HAART) show significant metabolic symptoms, such as lipodystrophy, dyslipidemia, and insulin resistance. A possible contribution to these symptoms in HIV/HAART is a decrease in mitochondrial function, resulting in a decreased fatty acid oxidation. A combined regime of aerobic and resistance training has been demonstrated to increase lean body mass and reduce overall fat and truncal fat and the levels of triglyceride and LDL cholesterol.
Conditions
- HIV Infections
- Hyperlipidemia
- Exercise
Interventions
- DIETARY_SUPPLEMENT
-
l-carnitine
3 gram daily dose
Sponsors & Collaborators
-
University of California, Davis
lead OTHER
Principal Investigators
-
Lars Berglund, MD, PhD · UC Davis Health System
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-07-31
- Primary Completion
- 2010-12-31
- Completion
- 2010-12-31
Countries
- United States
Study Locations
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