Comparison of Effectiveness and Costs of Post-diagnosis Treatment in Dementia

Summary

In the Netherlands a rapidly increasing number of multidisciplinary memory clinics (MMC) currently diagnose 25% of the patients with dementia. Following the diagnostic work-up, MMCs are increasingly involved in post-diagnosis treatment and coordination of care, which probably is very important for patients and caregivers, but also very time consuming and expensive. This study will focus on the important question whether this complex post-diagnosis treatment and care coordination, evaluated both on effectiveness and costs, should be carried out by MMCs (intervention) or by General Practitioners (GPs) (control) as pivot of delivery of health care for these patients.

Objectives: To determine MMCs' effectiveness and cost-effectiveness in post-diagnosis treatment and care-coordination for dementia-patients and their caregivers compared to the post-diagnosis treatment and care coordination by GPs.

Time schedule: 12 months for including patients and their caregivers and 12 months of follow-up.

Annex Study: Specifically for the Health Technology Assessment (HTA) methodology study the main study will be extended with some experimental proxy measurements and alternative measurement approaches.

The objective of this Annex-study is to explore the feasibility and validity of Health Related Quality of Life (HRQL) value measurement in dementia patients. And to study the characteristics of proxy rating in HRQL research in dementia and the suitability and validity of yielding HRQL measurements by proxy assessment. Furthermore to explore the validity, reliability, and feasibility of the EQ5D and EQ6D in dementia research (in patients and in/by proxies); response shift, and alternative (more simple) methods of HRQL measurement and validate the Dutch versions of the QOL-AD and the use of the CarerQol-7D in dementia research.

Conditions

• Dementia

Interventions

OTHER

Multidisciplinary Memory Clinic

Post-diagnosis treatment and coordination of care for patients with dementia and their informal caregivers delivered by Multidisciplinary Memory Clinics (MMCs)

OTHER

General Practitioners

Post-diagnosis treatment and coordination of care for patients with dementia and their informal caregivers delivered by general practitioners

Sponsors & Collaborators

• ZonMw: The Netherlands Organisation for Health Research and Development

  collaborator OTHER

• Netherlands Alzheimer Foundation

  collaborator OTHER

• Amsterdam UMC, location VUmc

  collaborator OTHER

• Maastricht University Medical Center

  collaborator OTHER

• Karolinska Institutet

  collaborator OTHER

• Stockholm Health Economics AB

  collaborator UNKNOWN

• Slingeland Hospital

  collaborator OTHER

• Elkerliek Hospital

  collaborator OTHER

• Ggz Oost Brabant

  collaborator OTHER

• Rijnstate Hospital

  collaborator OTHER

• Radboud University Medical Center

  lead OTHER

Principal Investigators

• Prof. Dr. M. Olde Rikkert, MD PhD · University Medical Centre St Radboud, Nijmegen

Study Design

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

SINGLE

Model

PARALLEL

Eligibility

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2007-12-31

Completion

2010-07-31

Countries

• Netherlands

Study Locations