The Secondary Prevention Trial for Ischemic Stroke With DengzhanShengmai Capsule

Summary

In order to observe the secondary preventive effect of the Dengzhanshengmai capsule on ischemic stroke, the investigators hold the large randomized control trial (RCT). 3143 subjects are included in 83 clinical research centers all over China. The subjects are randomly grouped into two groups. The basic therapy included antiplatelet aggregation, stroke health education, management of blood pressure, blood lipid and blood glucose, etc. The treating group will take the compound Chinese Medicine Deng Zhan Sheng Mai capsule and the contrast group will take the placebo for twelve months. Then all of the subjects are visited on the 30th, 90th, 180th, 360th day after inclusion. The recurrence of stroke, cardiovascular events, and peripheral arterial events are observed.

Conditions

• Stroke

Interventions

DRUG

Dengzhan Shengmai capsule

Capsule, 0.18g, 2#, Bid\*1year

DRUG

placebo

Capsule, 0.18g, 2#, Bid\*1year

Sponsors & Collaborators

• Second Affiliated Hospital, School of Medicine, Zhejiang University

  collaborator OTHER

• Nanhai Hospital of Traditional Chinese Medicine

  collaborator OTHER

• People's hospital of Huizhou city

  collaborator UNKNOWN

• Taishan city hospital of TCM

  collaborator UNKNOWN

• Ruijin Hospital

  collaborator OTHER

• First Affiliated Hospital of Fujian Medical University

  collaborator OTHER

• Yangjiang City Hospital of TCM in Guangdong Province

  collaborator UNKNOWN

• Xinxing county hospital of TCM

  collaborator UNKNOWN

• Southern branch of yuexiu district hospital of TCM

  collaborator UNKNOWN

• Xinhui hospital of TCM of Jiangmen

  collaborator UNKNOWN

• Shanghai Pudong New Area People's Hospital

  collaborator OTHER

• People's hospital of Jianyang city

  collaborator UNKNOWN

• Luzhou Medical College

  collaborator OTHER

• Mianyang city hospital of TCM

  collaborator UNKNOWN

• Guangyuan city hospital of TCM of Sichuan Province

  collaborator UNKNOWN

• The Third Affiliated Hospital of Guangzhou Medical University

  collaborator OTHER

• Shunde district hospital of TCM

  collaborator UNKNOWN

• Shenzhen People's Hospital

  collaborator OTHER

• Anyue County Hospital of Traditional Chinese

  collaborator OTHER

• Chengdu Integrated TCM&Western Medicine Hospital

  collaborator UNKNOWN

• Guangzhou Red Cross Hospital

  collaborator OTHER

• Jiangsu Provincial People's Hospital

  collaborator OTHER

• Ankang Hospital of Traditional Chinese Medicine

  collaborator OTHER

• Qishan county hospital of shaanxi province

  collaborator UNKNOWN

• Zongrui Hospital

  collaborator OTHER

• First Affiliated Hospital of Xinjiang Medical University

  collaborator OTHER

• Lianyungang Chinese Medicine Hospital

  collaborator UNKNOWN

• Yufu City Hospital of TCM in Guangdong Province

  collaborator UNKNOWN

• 169 Military Hospital of China

  collaborator OTHER

• Affiliated Hospital of Liaoning University of Traditional Chinese Medicine

  collaborator OTHER

• The second affiliated hospital of shanxi college of TCM

  collaborator UNKNOWN

• URUMQI Hospital of Traditional Chinese Medicine

  collaborator UNKNOWN

• Hubei General Hospital

  collaborator UNKNOWN

• The People's Hospital of Leshan

  collaborator OTHER

• Guagnzhou Liwan district Hospital of TCM

  collaborator UNKNOWN

• Longhua Hospital

  collaborator OTHER

• Shanghai Jiao Tong University School of Medicine

  collaborator OTHER

• Hangzhou City Hospital of TCM

  collaborator UNKNOWN

• Dongguan city hospital of TCM

  collaborator UNKNOWN

• Liuzhou City hospital of TCM

  collaborator UNKNOWN

• Maoming city hospital of TCM

  collaborator UNKNOWN

• Beijing Tiantan Hospital

  collaborator OTHER

• Affiliated Hospital of Nantong University

  collaborator OTHER

• Xi'an city hospital of TCM

  collaborator UNKNOWN

• Jiangsu province hospital of TCM

  collaborator UNKNOWN

• The Third People's Hospital of Chengdu

  collaborator OTHER

• Huizhou Municipal Central Hospital

  collaborator OTHER

• Zhejiang Provincial Hospital of TCM

  collaborator OTHER

• The Second People's Hospital of Yibin

  collaborator OTHER

• Shanxi Provincial People's Hospital

  collaborator OTHER_GOV

• The First Affiliated Hospital of Guangzhou Medical University

  collaborator OTHER

• Guangxi Ruikang Hospital

  collaborator OTHER

• Third Affiliated Hospital, Sun Yat-Sen University

  collaborator OTHER

• First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

  collaborator OTHER

• Affiliated Hospital of North Sichuan Medical College

  collaborator OTHER

• Third Affiliated Hospital of Henan University of Traditional Chinese Medicine

  collaborator OTHER

• ZhuHai Hospital

  collaborator OTHER

• Nanfang Hospital, Southern Medical University

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• Guangdong Second Provincial Traditional Chinese Medicine Hospital

  collaborator INDUSTRY

• Handan First Hospital

  collaborator OTHER

• The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine

  collaborator OTHER

• Conghua city hospital of TCM

  collaborator UNKNOWN

• The First Affiliated Hospital of Guangxi University of Chinese Medicine

  collaborator UNKNOWN

• Hubei Hospital of Traditional Chinese Medicine

  collaborator OTHER

• Jinan city hospital of TCM

  collaborator UNKNOWN

• Shaanxi Hospital of Traditional Chinese Medicine

  collaborator OTHER

• Suining People's Hospital

  collaborator UNKNOWN

• Wuzhou Red Cross Hospital

  collaborator OTHER

• Wuhan Interated ＆Western Hospital

  collaborator UNKNOWN

• Second Affiliated Hospital of Xi'an Jiaotong University

  collaborator OTHER

• Xi'an Central Hospital

  collaborator OTHER

• Zhengzhou City Hospital of Traditional Chinese Medicine

  collaborator OTHER

• Xiangya Hospital of Central South University

  collaborator OTHER

• Second Affiliated Hospital, Sun Yat-Sen University

  collaborator OTHER

• The First Affiliated Hospital of Henan University of Traditional Chinese Medicine

  collaborator OTHER

• ShuGuang Hospital

  collaborator OTHER

• Zhongshan Hospital Of Traditional Chinese Medicine

  collaborator OTHER

• Foshan Hospital of Traditional Chinese Medicine

  collaborator OTHER

• Teaching Hospital of Chengdu University of TCM

  collaborator UNKNOWN

• Jiangmen Wuyi Hospital of Traditional Chinese Medicine

  collaborator OTHER

• Guangdong Provincial Hospital of Traditional Chinese Medicine

  collaborator OTHER

• Guangzhou University of Traditional Chinese Medicine

  lead OTHER

Principal Investigators

• Yan Huang, Bachelor · Guangdong Provincial Hospital of Tradtional Chinese Medicine

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Model

PARALLEL

Eligibility

Min Age

40 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2007-12-31

Primary Completion

2011-01-31

Completion

2011-01-31

Countries

• China

Study Locations