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COGNITIVE - Cognitive Function After Sevoflurane or Propofol Anesthesia for Open-heart Operations

NCT00541918 · Status: WITHDRAWN · Phase: PHASE4 · Type: INTERVENTIONAL

Last updated 2015-10-28

No results posted yet for this study

Summary

The aim of the study is to prove whether general anesthesia with inhaled sevoflurane reduces the frequency of neurological and cognitive impairment after open-heart operations with use of cardiopulmonary by-pass (CPB) in comparison with intravenous anesthesia with propofol.

Conditions

  • Other Functional Disturbances Following Cardiac Surgery
  • Memory Disorders

Interventions

DRUG

Diprivan (propofol, Astra Zeneca)

Total intravenous anesthesia with propofol

DRUG

Sevorane (sevoflurane, Abbott)

inhaled anesthesia with sevoflurane

Sponsors & Collaborators

  • Medical University of Gdansk

    lead OTHER

Principal Investigators

  • Romuald Lango, M.D., Ph.D. · Medical University of Gdańsk, Department of Cardiac Anesthesiology

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
55 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-06-30
Primary Completion
2015-04-30
Completion
2015-04-30

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00541918 on ClinicalTrials.gov