Effectiveness of the Selective Serotonin Reuptake Inhibitor,Citalopram (Cipralex), in Prurigo Nodularis
NCT00532519 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL
Last updated 2007-09-20
Summary
Prurigo nodularis (PN) is a common dermatological disorder, manifested as scaly nodules which appear mainly on the extensor surfaces of the limbs. PN may appear secondarily to skin scratching in chronic hepatitis, liver cirrhosis, uremia, hypothyroidism etc. Nevertheless, in many cases no underlying physical disease is present. According to the literature, in fifty percent of the patients there is co-morbidity with depression, anxiety or somatoform disorders.
We hypothesize that a group of these patients may benefit from antidepressant therapy.
Conditions
- Prurigo Nodularis
Interventions
- DRUG
-
citalopram (cipralex)
10-20 mg/day, for 12 weeks.
Sponsors & Collaborators
-
Hadassah Medical Organization
lead OTHER
Principal Investigators
-
liran horev, md · Hadassah Medical Organization
-
rena cooper-kazaz, md · Hadassah Medical Organization
Study Design
- Allocation
- NA
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
Countries
- Israel
Study Locations
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