Citalopram Versus Citalopram Plus Pindolol in Major Depressive Disorder
NCT00931775 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2009-07-02
Summary
The purpose of this study is to examine whether the speed of the clinical antidepressant action of citalopram can be accelerated by administering double doses of pindolol (15 mg/day, tid) which presumably should lead to increased 5-HT1A autoreceptor occupancy.
Conditions
- Major Depressive Disorder
- Antidepressant Treatment Response
Interventions
- DRUG
-
Pindolol
Pill orally administered. 15 mg/day t.i.d.
Sponsors & Collaborators
-
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
lead OTHER
Principal Investigators
-
Enric Álvarez, MD, PhD · Department of Psychiatry. Hospital de la Santa Creu i Sant Pau
-
Víctor Pérez, MD, PhD · Department of Psychiatry. Hospital de la Santa Creu i Sant Pau
-
Francesc Artigas, PhD · Neurochemistry department. Consejo Superior de Investigaciones Científicas
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-12-31
- Primary Completion
- 2005-03-31
- Completion
- 2005-11-30
Countries
- Spain
Study Locations
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