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Early Detection and Intervention for the Prevention of Psychosis

NCT00531518 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 292

Last updated 2016-08-15

Study results available
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Summary

EDIPP is a multisite trial of early identification and intervention to prevent the onset of psychosis in adolescents and young adults, carried out at six sites across the United States. The hypothesis is that very early identification and intervention will be effective in delaying or preventing onset of psychosis and improving social and occupational functioning.

Conditions

Interventions

DRUG

aripiprazole; fluoxetine; bupropion; sertraline; lamotrigine

Oral, daily, generally at lower than manufacturer's recommendations

BEHAVIORAL

Psychoeducational multifamily group treatment

Families and patients are educated on psychobiology of psychosis and trained in coping skills to avoid psychosis by reducing stress and optimizing social environment at home, school, work

BEHAVIORAL

Supported employment and education

Participants are provided direct assistance, guidance and ongoing support to gain employment and succeed in their educational goals.

Sponsors & Collaborators

  • Robert Wood Johnson Foundation

    collaborator OTHER

  • MaineHealth

    lead OTHER

Principal Investigators

  • William R. McFarlane, M.D. · MaineHealth

Study Design

Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
12 Years
Max Age
25 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-10-31
Primary Completion
2013-05-31
Completion
2013-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00531518 on ClinicalTrials.gov