MedTrace Logo

The Natural History of Community-Associated MRSA Infections and Decolonization Strategies

NCT00513799 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2015-07-30

Study results available
· View outcomes & findings →

Summary

The purpose of this study is to determine the natural history of community-associated Staphylococcus aureus infections in both adult and pediatric patients by monitoring the rate of recurrent infections in those colonized with S. aureus.

In addition, this study will evaluate the efficiency of commonly prescribed decolonization measures in patients presenting with S. aureus skin and soft tissue infections.

Conditions

  • Abscesses
  • Furunculosis
  • Staphylococcus Aureus
  • Staphylococcal Skin Infections

Interventions

DRUG

Mupirocin ointment

Add a small amount of Mupirocin to the cotton end of a swab. Swab in inner nostril, then repeat in other nostril using new cotton swab with ointment. Twice daily treatment for 5 days.

GENETIC

Chlorhexidine showers

Apply Clorhexidine wash to entire body once daily for 5 days.

PROCEDURE

Bleach baths (dilute)

Pour 2 ounces of bleach into water-filled bath tub. Soak in bath for 15 minutes. Apply once daily for 5 days.

BEHAVIORAL

Intensive education on personal hygiene

Repeat hygiene methods for 5 days.

Sponsors & Collaborators

  • Washington University School of Medicine

    lead OTHER

Principal Investigators

  • Bernard C. Camins, MD, MSCR · Assistant Professor of Medicine, Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine

  • Gregory A. Storch, MD · Professor of Medicine and Molecular Microbiology, Chief of Division of Pediatric Infectious Diseases, Department of Medicine, Washington University School of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
6 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-03-31
Primary Completion
2009-06-30
Completion
2010-12-31

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00513799 on ClinicalTrials.gov