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Genes Causing Ebstein's Anomaly

NCT00497705 · Status: COMPLETED · Type: OBSERVATIONAL

Last updated 2017-07-02

No results posted yet for this study

Summary

This study will investigate Ebstein's anomaly, a congenital abnormality of the tricuspid valve of the heart and try to identify the genetic origins of the disease.

Adults and children 2 years of age and older with Ebstein's anomaly and healthy volunteers may be eligible for this study. Participants undergo the following procedures:

* Blood tests: Three tube of blood will be collected, with the total amount limited to about half a teaspon for each two pounds of body weight.
* Saliva sample collection: A small amount of saliva is collected by spitting into a sterile container.
* Oral (cheek) swab: Cells are collected from the mouth using a soft brush to swab the inside lining of the cheek.
* Electrocardiogram: The electrical activity of the heart is recorded using electrodes placed on the chest.
* Echocardiogram: Heart function is assessed using ultrasound.

Conditions

  • Heart Septal Defects, Ventricle
  • Heart Defects, Congenital
  • Double Outlet Right Ventricle
  • Truncus Arteriosus, Persistent

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    lead NIH

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-07-03
Primary Completion
2009-07-07

Countries

  • United States
  • Belarus
  • Ukraine

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00497705 on ClinicalTrials.gov