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dbGaP Protocol: Genetic Variants Associated With Pentalogy of Cantrell

NCT02430376 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3280

Last updated 2019-03-11

No results posted yet for this study

Summary

Background:

Pentalogy of Cantrell (POC) is a syndrome that involves many heart abnormalities as well as large defects in the chest and abdominal wall. This often results in the heart and other organs being present outside the body at birth. Surgeons have learned to replace them and repair the heart. Researchers want to find possible gene changes that cause POC. To do this, they want to study data from the Pediatric Cardiovascular Genetics Consortium (PCGC) Cohort. The PCGC collects data and DNA samples from people with heart diseases and their families

Objectives:

\- To find gene mutations in people with Pentalogy of Cantrell (POC) or other related syndromes.

Eligibility:

\- PCGC data and DNA samples that are open to study by the public.

Design:

* Researchers will study the data from the PCGC.
* The gene testing being done in this study was consented to in the original studies. No new consent or waiver request is required.
* The study will last 1 year.

Conditions

  • Pentalogy of Cantrell

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    lead NIH

Principal Investigators

  • Robert S Adelstein, M.D. · National Heart, Lung, and Blood Institute (NHLBI)

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-04-25
Primary Completion
2016-03-23
Completion
2016-03-23

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02430376 on ClinicalTrials.gov