Study to Evaluate Immune Responses in Neurologically Normal Cancer Patients
NCT00481637 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 33
Last updated 2019-04-17
Summary
The purpose of this study is to study whether immune cells capable of killing tumors that express proteins associated with paraneoplastic neurologic syndrome (PNS) can be found in small cell lung cancer and ovarian cancer patients. The presence of these cells may play a role in tumor immunity in these patients. The protocol involves neurological examinations and collection of blood.
Conditions
Sponsors & Collaborators
-
Rockefeller University
lead OTHER
Principal Investigators
-
Robert Darnell, MD, PHD · Rockefeller University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 1998-03-31
- Primary Completion
- 2013-05-31
- Completion
- 2013-05-31
Countries
- United States
Study Locations
More Related Trials
-
Phase 1, Open-label, Dose Escalation Study of TRC093, in Patients With Locally Advanced or Metastatic Solid Tumors
NCT00492830 ·Status: COMPLETED ·Phase: PHASE1
-
An Investigational Immuno-therapy Study of Experimental Medication BMS-986156, Given by Itself or in Combination With Nivolumab in Patients With Solid Cancers or Cancers That Have Spread.
NCT02598960 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Immunotherapy Combination: Irradiated PD-L1 CAR-NK Cells Plus Pembrolizumab Plus N-803 for Subjects With Recurrent/Metastatic Gastric or Head and Neck Cancer
NCT04847466 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of Immune Responses in Patients With Metastatic Melanoma
NCT01416844 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Study of MNRP1685A in Patients With Locally Advanced or Metastatic Solid Tumors
NCT00747734 ·Status: COMPLETED ·Phase: PHASE1
-
NM32-2668 in Adult Patients With Selected Advanced Solid Tumors
NCT06299163 ·Status: TERMINATED ·Phase: PHASE1
-
Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer
NCT05098210 ·Status: RECRUITING ·Phase: PHASE1
-
Serologic Response to the SARS-CoV-2 (COVID-19) MRNA-1273 Vaccine in Select Subsets of Oncology Patients
NCT04854980 ·Status: COMPLETED
-
A Study of IMC-002 in Patients With Advanced Cancer Failed to Standard Therapy
NCT05276310 ·Status: RECRUITING ·Phase: PHASE1
-
HER-2/Neu Vaccine Plus GM-CSF in Treating Patients With Stage III or Stage IV Breast, Ovarian, or Non-small Cell Lung Cancer
NCT00003002 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid Tumors
NCT04794972 ·Status: RECRUITING ·Phase: PHASE1
-
Peptide Vaccination for Patients at High Risk for Recurrent Melanoma
NCT00059475 ·Status: COMPLETED ·Phase: PHASE2
-
Nivolumab for the Treatment of Metastatic or Unresectable Solid Tumors With ARID1A Mutation and CXCL13 Expression
NCT04957615 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Vaccination of Melanoma Patients With Total or CD25-depleted Peripheral Blood Mononuclear Cell (PBMC)
NCT00961376 ·Status: TERMINATED ·Phase: PHASE2
-
An Open Label Investigational Immuno-therapy Trial of Nivolumab in Cancers That Are Advanced or Have Spread
NCT02832167 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluating the T Cell Response to a Peptide-based Vaccine in Patients With Breast Cancer
NCT00892567 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma.
NCT00688090 ·Status: COMPLETED ·Phase: PHASE1
-
Neoadj Admin Autologous Tumor Infiltrating Lymphocytes & Pembrolizumab for Treatment of Adv Melanoma Patients
NCT05176470 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Cancer Vaccine (CG8123) Given With and Without Cyclophosphamide for Advanced Stage Non-Small Cell Lung Cancer (NSCLC)
NCT00089726 ·Status: COMPLETED ·Phase: PHASE2
-
An Immunogenic Personal Neoantigen Vaccine for Cancer Treatment
NCT04087252 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of MEDI9197 in Subjects With Solid Tumors or CTCL and in Combination With Durvalumab and/or Palliative Radiation in Subjects With Solid Tumors
NCT02556463 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Melanoma
NCT07288203 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Phase I Study With a Personalized NeoAntigen Cancer Vaccine in Melanoma
NCT01970358 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Neoantigen mRNA Personalised Cancer in Patients With Advanced Solid Tumors
NCT05198752 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of IMC-002 in Subjects With Metastatic or Locally Advanced Solid Tumors and Relapsed or Refractory Lymphomas
NCT04306224 ·Status: COMPLETED ·Phase: PHASE1