An Open Label Investigational Immuno-therapy Trial of Nivolumab in Cancers That Are Advanced or Have Spread
NCT02832167 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 239
Last updated 2022-05-09
Summary
The purpose of this study is to determine whether nivolumab is an effective treatment for cancer that has advanced or has spread. Various tumor types may be eligible for enrollment.
Conditions
Interventions
- BIOLOGICAL
-
Specified dose on specified days
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Bristol-Myers Squibb · Bristol-Myers Squibb
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-02-22
- Primary Completion
- 2019-10-20
- Completion
- 2021-06-24
- FDA Drug
- Yes
Countries
- United States
- Germany
Study Locations
More Related Trials
-
Nivolumab for the Treatment of Metastatic or Unresectable Solid Tumors With ARID1A Mutation and CXCL13 Expression
NCT04957615 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma
NCT03220009 ·Status: WITHDRAWN ·Phase: PHASE2
-
Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas
NCT02304458 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Nivolumab in Treating Patients With Stage IIB-IIC Melanoma That Can Be Removed by Surgery
NCT03405155 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma
NCT02339571 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
Nivolumab in Treating Patients With Metastatic Adrenocortical Cancer
NCT02720484 ·Status: TERMINATED ·Phase: PHASE2
-
Nivolumab Alone or in Combination With Ipilimumab in Treating Patients With Advanced Uterine Leiomyosarcoma
NCT02428192 ·Status: COMPLETED ·Phase: PHASE2
-
Immunotherapy Combination: Irradiated PD-L1 CAR-NK Cells Plus Pembrolizumab Plus N-803 for Subjects With Recurrent/Metastatic Gastric or Head and Neck Cancer
NCT04847466 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer
NCT05098210 ·Status: RECRUITING ·Phase: PHASE1
-
Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers
NCT04416568 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Secured Access to Nivolumab for Adult Patients With Selected Rare Cancer Types
NCT03012581 ·Status: COMPLETED ·Phase: PHASE2
-
A Personal Cancer Vaccine (NEO-PV-01) w/ Nivolumab for Patients With Melanoma, Lung Cancer or Bladder Cancer
NCT02897765 ·Status: COMPLETED ·Phase: PHASE1
-
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
NCT02834013 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors
NCT03645928 ·Status: TERMINATED ·Phase: PHASE2
-
Nivolumab for Recurrent/Metastatic Carcinosarcoma
NCT05224999 ·Status: UNKNOWN ·Phase: PHASE2
-
A Phase 1 Study of Nivolumab (BMS-936558) in Subjects With Advanced or Recurrent Malignancies
NCT00730639 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of Denosumab in Combination With Immune Checkpoint Inhibitors in Patients With Unresectable or Metastatic Melanoma
NCT03161756 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery
NCT05111574 ·Status: RECRUITING ·Phase: PHASE2
-
Nivolumab and Ipilimumab in Treating Patients With Metastatic Uveal Melanoma
NCT01585194 ·Status: COMPLETED ·Phase: PHASE2
-
Testing Treatment With Ipilimumab and Nivolumab Compared to Treatment With Ipilimumab Alone in Advanced Melanoma
NCT03033576 ·Status: COMPLETED ·Phase: PHASE2
-
Gene-Modified T Cells, Vaccine Therapy, and Nivolumab in Treating Patients With Stage IV or Locally Advanced Solid Tumors Expressing NY-ESO-1
NCT02775292 ·Status: COMPLETED ·Phase: PHASE1
-
Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors
NCT05629546 ·Status: RECRUITING ·Phase: PHASE1
-
An Investigational Immuno-Therapy Study of Experimental Medication BMS-986178 by Itself or in Combination With Nivolumab and/or Ipilimumab in Participants With Solid Cancers That Are Advanced or Have Spread
NCT02737475 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Malignancies
NCT04785287 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Phase II Trial of Nivolumab Plus Ipilimumab in Patients With Renal Medullary Carcinoma
NCT03274258 ·Status: TERMINATED ·Phase: PHASE2