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Exhaled Breath Condensate pH in Patients With Cough Caused by Gastroesophageal Reflux

NCT00451841 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2018-06-26

No results posted yet for this study

Summary

Cough is the most common complaint for which patients seek medical attention in the United States, accounting for approximately 1 billion dollars in health care expenses annually. Gastroesophageal reflux disease (GERD) is the sole cause of chronic cough in up to 20-40% of all cases. The majority of these patients with GERD-induced cough have no classic "heartburn" symptoms, so this important cause of cough can thus be difficult to detect.

Our hypothesis is that changes in exhaled breath condensate (EBC) pH can be used as a sensitive and non-invasive marker to identify subjects with cough caused by acid reflux.

Conditions

  • Cough
  • Gastroesophageal Reflux

Interventions

DEVICE

RTube Exhaled Breath Condensate Collection System

Subjects breath through the device to collect exhaled breath condensate

Sponsors & Collaborators

  • University of Massachusetts, Worcester

    lead OTHER

Principal Investigators

  • Stephen Krinzman, MD · University of Massachusetts, Worcester

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-03-31
Primary Completion
2013-06-30
Completion
2013-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00451841 on ClinicalTrials.gov