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Statins to Reduce D-dimer Levels in Patients With Venous Thrombosis

NCT00437892 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2011-08-19

No results posted yet for this study

Summary

Elevated levels of D-dimer, a marker of procoagulant state, have been identified as a marker of an increased risk of recurrent VTE. Statins have proven antithrombotic properties, as suggested by the reduction of several prothrombotic markers, including D-dimer, in patients at high risk of arterial thrombosis. Such antithrombotic properties could also be observed in patients at high risk of venous thrombosis. Aim of the study is to assess the effect of statins on D-dimer levels in patients with previous VTE after oral anticoagulant treatment withdrawal.

Conditions

Interventions

DRUG

atorvastatin

tablets, 40 mg day, 3 months

DRUG

atorvastatin

tablets, 40 mg once daily

BEHAVIORAL

diet

daily

BEHAVIORAL

diet

daily diet

Sponsors & Collaborators

  • Università degli Studi dell'Insubria

    lead OTHER

Principal Investigators

  • Walter Ageno · Università degli Studi dell'Insubria

  • Gualtiero Palareti · University of Bologna

  • Davide Imberti · Piacenza Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-05-31
Primary Completion
2011-05-31
Completion
2011-05-31

Countries

  • Italy

Study Locations

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Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00437892 on ClinicalTrials.gov