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Gas Supply, Demand and Middle Ear Gas Balance: Specific Aim 3c

NCT00422851 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 45

Last updated 2017-11-13

No results posted yet for this study

Summary

This study will determine if gas can pass between the environment and the middle ear by way of the eardrum. This route of gas exchange was observed in animals but has not been studied in humans. If gas exchange across the eardrum is documented and the rate is sufficiently high, this can help explain certain past observations such as why middle ear pressure does not change very much in some children and adults when they have a cold or flu. The investigators also expect that the rate of gas exchange across the eardrum will depend on whether or not the eardrum has scarred or abnormally thin regions.

Conditions

  • Healthy

Sponsors & Collaborators

  • National Institute on Deafness and Other Communication Disorders (NIDCD)

    collaborator NIH

  • University of Pittsburgh

    lead OTHER

Principal Investigators

  • William Doyle, PhD · University of Pittsburgh

  • J. Douglas Swarts, PhD · University of Pittsburgh

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-06-30
Completion
2009-02-28

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00422851 on ClinicalTrials.gov