VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer
NCT00407654 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 75
Last updated 2024-03-04
Summary
This phase II trial is studying how well VEGF Trap works in treating patients with previously treated metastatic colorectal cancer. VEGF Trap may stop the growth of colorectal cancer by blocking blood flow to the tumor.
Conditions
- Recurrent Colon Cancer
- Recurrent Rectal Cancer
- Stage IV Colon Cancer
- Stage IV Rectal Cancer
Interventions
- DRUG
-
Given intravenously
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Malcolm Moore · University Health Network-Princess Margaret Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-10-31
- Primary Completion
- 2012-09-30
- Completion
- 2012-09-30
Countries
- Canada
Study Locations
More Related Trials
-
Study of Bevacizumab, Erlotinib, FOLFOX for Patients With Untreated Metastatic Colorectal Cancer
NCT00116506 ·Status: COMPLETED ·Phase: PHASE2
-
S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer
NCT02164916 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan in Treating Patients With Metastatic Colorectal Cancer
NCT00003544 ·Status: COMPLETED ·Phase: PHASE2
-
Bevacizumab Plus Fluorouracil and Leucovorin in Treating Patients With Locally Advanced or Metastatic Stage IV Colorectal Cancer That Has Progressed After Standard Chemotherapy
NCT00066846 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II Study of Gemcitabine and Capecitabine for Treatment Resistant, Metastatic Colorectal Cancer
NCT01472770 ·Status: COMPLETED ·Phase: PHASE2
-
Capecitabine and Bevacizumab With or Without Atezolizumab in Treating Patients With Refractory Metastatic Colorectal Cancer
NCT02873195 ·Status: COMPLETED ·Phase: PHASE2
-
Bevacizumab and Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer
NCT00544011 ·Status: UNKNOWN ·Phase: PHASE2
-
Monoclonal Antibody Therapy in Treating Patients With Advanced Colorectal Cancer
NCT00027729 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Monoclonal Antibody Therapy and Colony- Stimulating Factor in Treating Patients With Metastatic Colorectal Cancer
NCT00002664 ·Status: WITHDRAWN ·Phase: PHASE2
-
Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery
NCT01802320 ·Status: COMPLETED ·Phase: PHASE2
-
Gene Expression in Patients With Advanced or Metastatic Colorectal Cancer Receiving Bevacizumab
NCT00897754 ·Status: COMPLETED
-
Cetuximab and Irinotecan in Treating Patients With Advanced Colorectal Cancer
NCT00005076 ·Status: COMPLETED ·Phase: PHASE2
-
Modulation Of The Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise With PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer
NCT03647839 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate U3-1402 in Subjects With Advanced or Metastatic Colorectal Cancer
NCT04479436 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Ticilimumab in Patients With Metastatic Colorectal Cancer Whose Disease Had Progressed After Treatment
NCT00313794 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Micrometastases in Patients With Stage I or Stage II Localized Colon Cancer That Can Be Removed by Surgery
NCT01097265 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Irofulven in Treating Patients With Metastatic or Recurrent Colorectal Cancer
NCT00003786 ·Status: WITHDRAWN ·Phase: PHASE2
-
Bevacizumab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery
NCT00467142 ·Status: COMPLETED ·Phase: PHASE2
-
ZD6474, Cetuximab, and Irinotecan in Patients With Metastatic Colorectal Cancer
NCT00436072 ·Status: COMPLETED ·Phase: PHASE1
-
AZD0530 (NSC 735464) in Treating Patients With Previously Treated Metastatic Colon Cancer or Rectal Cancer
NCT00397878 ·Status: TERMINATED ·Phase: PHASE2
-
Study Using CP-751,871 In Patients With Stage IV Colorectal Cancer That Has Not Responded To Previous Anti-Cancer Treatments
NCT00560560 ·Status: COMPLETED ·Phase: PHASE2
-
Monoclonal Antibody Therapy and/or Vaccine Therapy in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer
NCT00007826 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Tocotrienol and Bevacizumab in Metastatic Colorectal Cancer
NCT04245865 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Phase II Study of Zaltrap and Chemotherapy for Advanced Resectable Colorectal Cancer
NCT02046538 ·Status: WITHDRAWN ·Phase: PHASE2
-
Clinical And Translational Study Of MK-2206 In Patients With Metastatic KRAS-Wild-Type, PIK3CA-Mutated, Colorectal Cancer
NCT01186705 ·Status: TERMINATED ·Phase: PHASE2