Irofulven in Treating Patients With Metastatic or Recurrent Colorectal Cancer
NCT00003786 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2014-03-07
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of irofulven in treating patients with metastatic or recurrent colorectal cancer.
Conditions
Interventions
- DRUG
-
irofulven
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
University of Chicago
lead OTHER
Principal Investigators
-
Hedy L. Kindler, MD · University of Chicago
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-04-30
- Primary Completion
- 2000-11-30
- Completion
- 2000-11-30
Countries
- United States
Study Locations
More Related Trials
-
Irinotecan in Treating Patients With Metastatic Colorectal Cancer
NCT00003544 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan and Cyclosporine in Treating Patients With Metastatic, Advanced or Locally Recurrent Colorectal Cancer
NCT00003950 ·Status: COMPLETED ·Phase: PHASE2
-
For Prevention of Diarrhea in Patients Diagnosed With Metastatic Colorectal Cancer Treated With Chemotherapy
NCT00037180 ·Status: TERMINATED ·Phase: PHASE2
-
NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer
NCT00856375 ·Status: COMPLETED ·Phase: PHASE2
-
ISIS 2503 in Treating Patients With Metastatic and/or Locally Recurrent Colorectal Cancer
NCT00004193 ·Status: TERMINATED ·Phase: PHASE2
-
S9923 R115777 in Treating Patients With Advanced Colorectal Cancer
NCT00005833 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Bevacizumab, Erlotinib, FOLFOX for Patients With Untreated Metastatic Colorectal Cancer
NCT00116506 ·Status: COMPLETED ·Phase: PHASE2
-
Regorafenib and Pembrolizumab in Treating Participants With Advanced or Metastatic Colorectal Cancer
NCT03657641 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Erlotinib in Treating Patients With Recurrent or Metastatic Colorectal Cancer
NCT00032110 ·Status: COMPLETED ·Phase: PHASE2
-
ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer
NCT01675128 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of Irinotecan Plus Capecitabine to Treat Advanced Colorectal Cancer
NCT01322152 ·Status: COMPLETED ·Phase: PHASE2
-
RO4929097 in Treating Patients With Metastatic Colorectal Cancer
NCT01116687 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Study of Irinotecan,Oxaliplatin Plus TS-1 in Untreated Metastatic Colorectal Cancer
NCT00506571 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Ruxolitinib in Colorectal Cancer Patients
NCT02119676 ·Status: TERMINATED ·Phase: PHASE2
-
Irinotecan With or Without Capecitabine as Second-Line Therapy in Treating Older Patients With Progressive, Metastatic Colorectal Cancer That Cannot Be Removed By Surgery
NCT00303745 ·Status: UNKNOWN ·Phase: PHASE2
-
A Real-World Study to Learn More About the Order of Different Treatments and Their Effects in People With Metastatic Colorectal Cancer Receiving Their Third and Fourth Line of Treatment
NCT06137170 ·Status: COMPLETED
-
SarCNU in Treating Patients With Recurrent or Metastatic Colorectal Cancer
NCT00028015 ·Status: COMPLETED ·Phase: PHASE2
-
Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer
NCT04117945 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Trial of Perioperative CV301 Vaccination in Combination With Nivolumab and Systemic Chemotherapy for Metastatic CRC
NCT03547999 ·Status: TERMINATED ·Phase: PHASE2
-
Radiation Therapy Plus Irinotecan in Treating Patients With Colon Cancer
NCT00003344 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread
NCT03377361 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Phase 2 Randomized, Open-Label Study of RRx-001 vs Regorafenib in Subjects With Metastatic Colorectal Cancer
NCT02096354 ·Status: COMPLETED ·Phase: PHASE2
-
S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer
NCT02164916 ·Status: COMPLETED ·Phase: PHASE2
-
Utomilumab, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Metastatic Colorectal Cancer
NCT03290937 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Irinotecan With Dabrafenib Plus Trametinib and Anti-EGFR in the Second Line of Therapy in People With Metastatic Colorectal Cancer
NCT06967155 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2