Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe Sepsis
NCT00406198 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 400
Last updated 2006-12-04
Summary
The impact of continuous veno-venous haemofiltration (CVVH) on sepsis-induced multiple organ failure severity is controversial. We thus sought to assess the effect of early application of haemofiltration on the degree of organ dysfunction and plasma cytokine levels in patients with severe sepsis or septic shock.
Conditions
- Bacteremia
- Gram-Negative Bacterial Infections
- Gram-Positive Bacterial Infections
- Pneumonia, Bacterial
- Shock, Septic
- Sepsis
Interventions
- PROCEDURE
-
venovenous hemofiltration
Sponsors & Collaborators
-
Ministry of Health, France
collaborator OTHER_GOV -
Hopital Lariboisière
lead OTHER
Principal Investigators
-
Didier Payen, MD, PhD · Hpopital Lariboisiere
Study Design
- Allocation
- RANDOMIZED
- Purpose
- SUPPORTIVE_CARE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1997-03-31
- Completion
- 1999-12-31
Countries
- France
Study Locations
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