A Study of the Effect of INCB013739 on Cortisone Reducing Enzyme Activity in Obese People Predisposed to Diabetes
NCT00398619 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2012-01-23
Summary
The purpose of this study is to determine whether the investigational drug INCB013739 has an effect on systemic and adipose tissue 11-HSD1 activity in obese, insulin resistant subjects.
Conditions
Interventions
- DRUG
-
INCB13739
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
William V Williams, MD · Incyte Corporation
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-11-30
- Primary Completion
- 2007-03-31
- Completion
- 2007-03-31
Countries
- United States
Study Locations
More Related Trials
-
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
NCT06845202 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Study to Evaluate Methods That Assess the Effect of AZD4017 in Adipose Tissue
NCT01096004 ·Status: COMPLETED ·Phase: PHASE1
-
Study of INV-202 in Patients With Obesity and Metabolic Syndrome
NCT05891834 ·Status: COMPLETED ·Phase: PHASE2
-
A 2-Year Study of an Investigational Drug in Obese Patients (0557-011)
NCT00092859 ·Status: COMPLETED ·Phase: PHASE3
-
Tirzepatide Use in People With Obesity and Type 1 Diabetes
NCT07096908 ·Status: RECRUITING ·Phase: PHASE4
-
A 1-Year Study On The Effects Of CP-945,598 For The Treatment Of Obesity In Overweight Type 2 Diabetic Patients
NCT00391196 ·Status: TERMINATED ·Phase: PHASE3
-
Evaluate the Efficacy and Safety of NT-0796 in Participants With Obesity With or Without Type 2 Diabetes Mellitus
NCT07055516 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Phase 1 Study of CT-996 in Overweight/Obese Participants and Patients With Type 2 Diabetes Mellitus
NCT05814107 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of CT-868 in Overweight and Obese Participants With Type 2 Diabetes Mellitus
NCT05110846 ·Status: COMPLETED ·Phase: PHASE2
-
An Investigational Drug Study in Obese (Considerably Overweight) Patients (0364-006)
NCT00109148 ·Status: COMPLETED ·Phase: PHASE2
-
Single and Multiple Ascending Dose Study of AMG 513 in Participants With Obesity
NCT06585462 ·Status: RECRUITING ·Phase: PHASE1
-
Safety and Efficacy Study of LIPO-202 for the Reduction of Central Abdominal Bulging in Obese Subjects
NCT02568319 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Tirzepatide on Brown Adipose Tissue in Obesity
NCT06893211 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Tolerance and Pharmacokinetic Study of Trodusquemine in Healthy Volunteers
NCT00509132 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Determine the Effects of TM30339 on Weight Loss in Obese Individuals.
NCT00746824 ·Status: TERMINATED ·Phase: PHASE2
-
A Study Of 6-Month Duration To Evaluate The Weight Loss Effect Of Various Doses Of CP-945,598 In Obese Subjects
NCT00134199 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Effect of Momordica Charantia Administration on Anthropometric Indicators in Patients With Obesity
NCT04916379 ·Status: UNKNOWN ·Phase: NA
-
Multiple Dose Study Of PF-05231023 In Obese Adult Subjects
NCT01923389 ·Status: TERMINATED ·Phase: PHASE1
-
A Phase 1/2 Study to Evaluate ALN-KHK in Overweight to Obese Healthy Volunteers and Obese Patients With T2DM
NCT05761301 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A 2-part, Phase 1b Clinical Study Designed to Evaluate the Safety, PK, and Efficacy of CRB-913 in Participants With Obesity
NCT07310901 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of Enicepatide (CT-388) in Participants Who Are Overweight or Obese With Type 2 Diabetes Mellitus
NCT06628362 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of ABBV-295 Subcutaneous Injections to Assess Adverse Events and Pharmacokinetics in Adult Participants With Obesity
NCT07291232 ·Status: RECRUITING ·Phase: PHASE1
-
Subcutaneously Administered MD-18 for the Treatment of Obesity and Diabetes
NCT06739707 ·Status: SUSPENDED ·Phase: PHASE1
-
DBRPC Study to Evaluate the Efficacy and Safety of IQP-AE-103 in Overweight and Moderately Obese Subjects
NCT04086797 ·Status: COMPLETED ·Phase: NA
-
A Study Evaluating the Effect of Daily Oral RO7795081 in Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity
NCT07081958 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2