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Xylitol Adult Caries Trial (X-ACT)

NCT00393055 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 709

Last updated 2011-09-12

No results posted yet for this study

Summary

The purpose of the trial is to determine the extent to which daily use of xylitol lozenges reduces the appearance of new caries lesions in adults who tend to experience such lesions (i.e., caries-active adults).

Conditions

  • Dental Caries

Interventions

DIETARY_SUPPLEMENT

xylitol

1g xylitol lozenges to be dissolved in mouth. Five lozenges daily for three years

DIETARY_SUPPLEMENT

inactive lozenge

1g inactive lozenge, dissolved in mouth. Five/day for three years

Sponsors & Collaborators

  • National Institute of Dental and Craniofacial Research (NIDCR)

    collaborator NIH

  • University of North Carolina, Chapel Hill

    lead OTHER

Principal Investigators

  • James D Bader, DDS MPH · UNC School of Dentistry

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
25 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-01-31
Primary Completion
2011-06-30
Completion
2011-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00393055 on ClinicalTrials.gov