Effect of Metformin on Lactate Metabolism
NCT00390273 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2008-10-07
Summary
The main objective of this study is to evaluate the influence of metformin on lactate metabolism.
The main outcome is the lactate production following an exogenous lactate overload in healthy male subjects without metformin and one week later with metformin.
Conditions
- Hyperlactatemia
Interventions
- DRUG
Sponsors & Collaborators
- collaborator INDUSTRY
-
Centre de Recherche en Nutrition Humaine Rhone-Alpe
lead OTHER
Principal Investigators
-
Eric Fontaine, Pr · University Hospital, Grenoble
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- FACTORIAL
Eligibility
- Min Age
- 18 Years
- Max Age
- 30 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2006-12-31
- Primary Completion
- 2007-10-31
- Completion
- 2007-10-31
Countries
- France
Study Locations
More Related Trials
-
Effects of Metformin Treatment on Myocardial Efficiency in Patients With Heart Failure
NCT02810132 ·Status: COMPLETED ·Phase: PHASE2
-
Incretin Hormones in Type 1 Diabetes Mellitus;Effect of Metformin Treatment
NCT04177303 ·Status: UNKNOWN ·Phase: PHASE3
-
Cardiovascular Effects of Metformin on Obesity
NCT01910246 ·Status: WITHDRAWN ·Phase: PHASE4
-
Metformin to Prevent Metabolic Complications in Glucocorticoid Excess
NCT01187849 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Human Leptin Replacement
NCT00657605 ·Status: COMPLETED ·Phase: PHASE2
-
Management of Diabetes With Metformin In Patients With Chronic Heart Failure
NCT01122316 ·Status: COMPLETED ·Phase: NA
-
CLINICAL PROTOCOL to Investigate the Long-term Safety and Efficacy of Metreleptin in Various Forms of Partial Lipodystrophy
NCT02654977 ·Status: COMPLETED ·Phase: PHASE2
-
Mifepristone Effects on Glucose Intolerance in Obese/Overweight Adults
NCT01419535 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Metformin Reduces Left Ventricular Mass in Patients With Ischemic Heart Disease
NCT01879293 ·Status: COMPLETED ·Phase: PHASE4
-
Metformin to Treat Corticosteroids-induced Hyperglycemia
NCT04332393 ·Status: COMPLETED ·Phase: PHASE4
-
MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes
NCT05065372 ·Status: RECRUITING ·Phase: PHASE1
-
The Role of GLP-1 Receptor Signalling in the Glucose-lowering Effect of Metformin in Patients With T2D
NCT03246451 ·Status: COMPLETED ·Phase: NA
-
Effect of Metformin and Cholecystokinin-mediated Gallbladder Emptying on GLP-1 Secretion in Type 2 Diabetes
NCT02497313 ·Status: COMPLETED ·Phase: NA
-
Prevention of Metabolic Complications of Glucocorticoid Excess
NCT01319994 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Quantification of the Incretin Effect in Healthy Subjects and Patients With Type 2 Diabetes
NCT00529048 ·Status: COMPLETED
-
The Effect of Addition of Metformin In Obese Non- Diabetic Patients With Heart Failure With Preserved Ejection Fraction
NCT05847244 ·Status: RECRUITING ·Phase: PHASE2
-
Effect of Metreleptin Therapy in the Treatment of Severe Insulin Resistance
NCT00085982 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Metformin to Treat Obesity in Children With Insulin Resistance
NCT00005669 ·Status: COMPLETED ·Phase: PHASE2
-
In Vitro Fertilization Impact on Metabolic Parameters
NCT03426228 ·Status: COMPLETED
-
Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy
NCT02262832 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Incretin Effect in Lean and Obese Subjects
NCT00803296 ·Status: COMPLETED
-
Investigating the Incretin Effect in Cystic Fibrosis
NCT01975259 ·Status: COMPLETED
-
Is Insulin Resistance and/or Glucose Intolerance Pathogenetic in the Development of a Reduced Incretin Effect
NCT00784745 ·Status: COMPLETED ·Phase: NA
-
A Pilot Study: Metformin Therapy in Heart Failure Patients With Early Diabetes or at High Risk of Developing Diabetes (Pre-Diabetes)
NCT01573949 ·Status: COMPLETED ·Phase: NA
-
Renal and Hormonal Effects of Pioglitazone
NCT01090752 ·Status: COMPLETED ·Phase: PHASE4