Effect Of Rilapladib (SB-659032) On Platelet Aggregation
NCT00387257 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 58
Last updated 2015-04-15
Summary
The purpose of this study is to compare the effects of repeat doses of SB-659032 with placebo on platelet aggregation in subjects.
Conditions
- Healthy Subjects
- Atherosclerosis
Interventions
- DRUG
-
Rilapladib (SB-659032)
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
GSK Clinical Trials · GlaxoSmithKline
Study Design
- Allocation
- RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2006-10-31
- Primary Completion
- 2007-04-30
- Completion
- 2007-04-30
Countries
- Australia
Study Locations
More Related Trials
-
Bioequivalence Study of Clopidogrel 75 mg in Two Tablet Formulations Relative to Reference Tablet in Healthy Subjects
NCT02502812 ·Status: COMPLETED ·Phase: PHASE1
-
ALBION "Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis"
NCT00360386 ·Status: COMPLETED ·Phase: PHASE2
-
Comparison of Platelet Inhibition With Adjunctive Cilostazol Versus High Maintenance-Dose Clopidogrel According to Hepatic Cytochrome 2C19 Allele (CYP2C19) Polymorphism
NCT00891670 ·Status: UNKNOWN ·Phase: PHASE3
-
A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome
NCT00391872 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of Edoxaban on Platelet Aggregation
NCT05122455 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Effects of Optimized Antiplatelet Treatment After Percutaneous Coronary Intervention
NCT00404781 ·Status: COMPLETED ·Phase: PHASE4
-
Mixed Antagonist of Serotonin for Claudication Optimal Therapy
NCT00300339 ·Status: COMPLETED ·Phase: PHASE2
-
Studying the Efficacy of Aspirin & Clopidogrel in Healthy Subjects With Stable Coronary Artery Disease.
NCT01011257 ·Status: WITHDRAWN ·Phase: PHASE4
-
Platelet-dependent Thrombosis: a Placebo-controlled Trial of Antiplatelet Therapy (Clopidogrel)
NCT00728156 ·Status: COMPLETED ·Phase: PHASE4
-
Safety Evaluation of Clopidogrel Sulfate in Patients With Peripheral Arterial Disease
NCT00862420 ·Status: COMPLETED ·Phase: PHASE3
-
Pharmacodynamic and Pharmacokinetic Study of 2 Different Dose Regimen of Clopidogrel in CYP2C19 Genotyped Healthy Subjects
NCT01123824 ·Status: COMPLETED ·Phase: PHASE1
-
Healthy Volunteer Study of Clopidogrel and Rifampicin
NCT00696566 ·Status: COMPLETED ·Phase: PHASE1
-
A Clinical Study to Assess the Effect of Clopidogrel on the Pharmacokinetics of Selexipag and Its Active Metabolite in Healthy Male Subjects
NCT03496506 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate Platlet Aggregation of Clopidogrel, EC Aspirin 81 mg, EC Omeprazole 40 mg Compare to PA32540
NCT01557335 ·Status: COMPLETED ·Phase: PHASE1
-
PACT (Platelet Activity After Clopidogrel Termination)
NCT00619073 ·Status: COMPLETED ·Phase: NA
-
Chewing Clopidogrel in Addition to Regular Oral Clopidogrel Treatment to Improve Platelets Aggregation in Patient With NON ST ELEVATION MI
NCT00889044 ·Status: UNKNOWN ·Phase: PHASE3
-
Reproducibility and Comparison of Platelet Function Assays With Aspirin and Clopidogrel (MK-0000-167)
NCT01108588 ·Status: COMPLETED ·Phase: PHASE1
-
Different Platelet Activities Between Intracoronary and Peripheral Blood in Coronary Artery Disease Patients
NCT03078257 ·Status: UNKNOWN ·Phase: PHASE1
-
Dual Antiplatelet Therapy (DAPT) in Patients With Baseline Thrombocytopenia
NCT06223607 ·Status: RECRUITING
-
Reversibility of Dual Antiplatelet Therapy by Platelets
NCT01248351 ·Status: COMPLETED ·Phase: PHASE2
-
The Inhibition of Platelet Antiaggregating Activity of Clopidogrel by Atorvastatin Detected by Erythromycin Breath Test: a Metabolic Inhibition of Hepatic Cytochrome P450-3A
NCT00004564 ·Status: UNKNOWN ·Phase: NA
-
A Study of the Onset and Offset of Antiplatelet Effects Comparing Ticagrelor, Clopidogrel, and Placebo With Aspirin
NCT00528411 ·Status: COMPLETED ·Phase: PHASE2
-
Platelet Function Assessment for Atherothrombotic Patients
NCT00513149 ·Status: UNKNOWN ·Phase: PHASE4
-
Efficacy and Safety in Patients With Acute Coronary Syndrome Without ST-Segment Elevation
NCT00325390 ·Status: COMPLETED ·Phase: PHASE3
-
Antiplatelet Resistance Research in Patients With Peripheral Arterial Revascularization
NCT03953547 ·Status: COMPLETED