Dual Antiplatelet Therapy (DAPT) in Patients With Baseline Thrombocytopenia
NCT06223607 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2024-01-25
Summary
The use of clopidogrel as part of DAPT will be associated with lower bleeding rates compared to ticagrelor in patients with chronic thrombocytopenia requiring Percutaneous intervention (PCI )with Drug Eluting Stent (DES) or Bare Metal Stint(BMS).
Conditions
- Baseline Thrombocytopenia
Sponsors & Collaborators
-
Methodist Health System
lead OTHER
Principal Investigators
-
Jessica Rago Crotty, Pharm D · Methodist Midlothian Medical Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-08-22
- Primary Completion
- 2024-08-22
- Completion
- 2024-08-22
Countries
- United States
Study Locations
More Related Trials
-
Genotype-Guided Abbreviated DAPT Versus Un-Guided De-escalation Therapy in Patients With ACS and HBR
NCT06763744 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Clopidogrel Versus Aspirin MOnotherapy After 1- to 3-month of Dual-antiplatelet thErapy Following Zotarolimus-eluting Onyx Stents Implantation; C-MODE Trial
NCT05320926 ·Status: RECRUITING ·Phase: NA
-
Platelet Reactivity After Receiving Clopidogrel Among Moderate CKD Patients Undergoing PCI
NCT02556671 ·Status: UNKNOWN
-
Genotype Guided Antiplatelet Therapy In Ischemic Stroke
NCT05763862 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Short-Term Dual Antiplatelet and Maintenance CloPidogrel Therapy After Drug-Eluting Stent Implantation
NCT02494284 ·Status: TERMINATED ·Phase: PHASE4
-
Ticagrelor and Clopidogrel on Platelet Effects in Chinese Patients With Stable Coronary Artery Disease
NCT04001894 ·Status: COMPLETED ·Phase: PHASE4
-
PACT (Platelet Activity After Clopidogrel Termination)
NCT00619073 ·Status: COMPLETED ·Phase: NA
-
Monitoring Antiplatelet Drugs in Cardiac Arrest Patients
NCT05730114 ·Status: UNKNOWN
-
Half-dose Ticagrelor Overcomes High-dose Clopidogrel in Acute Coronary Syndrome Patients With High On-Clopidogrel Platelet Reactivity
NCT03062462 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Tailoring Of Platelet Inhibition to Avoid Stent Thrombosis
NCT00914368 ·Status: COMPLETED ·Phase: PHASE2
-
Optimal Duration of Clopidogrel in Second-Generation Drug-Eluting Stents
NCT03056118 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of 1 Month vs. 12 Months DAPT in Patients Undergoing PCI With Genoss® DES
NCT05770674 ·Status: RECRUITING ·Phase: NA
-
Comparison Between P2Y12 Antagonist Monotherapy and Dual Antiplatelet Therapy After DES
NCT02079194 ·Status: UNKNOWN ·Phase: NA
-
A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome
NCT00391872 ·Status: COMPLETED ·Phase: PHASE3
-
Investigation of the Impact of Concomitant Use of Multiple Doses of Clopidogrel With Multiple Doses of Dabigatran Etexilate on the Pharmacokinetic and Pharmacodynamic Parameters in Healthy Male Subjects
NCT02171598 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1 Study to Evaluate the Safety and Tolerability of DS-1040b IV Infusion With Clopidogrel in Healthy Subjects
NCT02560688 ·Status: COMPLETED ·Phase: PHASE1
-
Ticagrelor vs Clopidogrel for Platelet Inhibition in Stenting for Cerebral Aneurysm
NCT02675205 ·Status: COMPLETED ·Phase: PHASE3
-
Genotype-guided Strategy for Antithrombotic Treatment in Peripheral Arterial Disease.
NCT04619927 ·Status: UNKNOWN ·Phase: PHASE4
-
Time Based Strategy to Reduce Clopidogrel Associated Bleeding Related to Coronary Artery Bypass Graft (CABG)
NCT00857155 ·Status: UNKNOWN ·Phase: NA
-
CYP2C19 Genotype-Guided P2Y12 Receptor Inhibitor Selection After Complex Percutaneous Coronary Intervention
NCT06283888 ·Status: RECRUITING ·Phase: PHASE4
-
Low Maintenance Dose Ticagrelor Versus Clopidogrel in Diabetes Patients Undergoing PCI
NCT03437044 ·Status: COMPLETED ·Phase: PHASE4
-
Ticagrelor and Clopidogrel on Platelet Aggregation in Clopidogrel Resistance's Patients With CHD
NCT03614832 ·Status: UNKNOWN ·Phase: PHASE4
-
Highest Efficacy of Dual Antiplatelet Therapy After Carotid Artery Stenting in High Bleeding Risk Patients
NCT06276374 ·Status: RECRUITING ·Phase: NA
-
Antiplatelet Strategy for Peripheral Arterial Interventions for Revascularization of Lower Extremities
NCT02217501 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of the Antiplatelet Effects Comparing Ticagrelor (Ticag. - AZD6140) With Clopidogrel (Clop.) Responder and Non-responders
NCT00642811 ·Status: COMPLETED ·Phase: PHASE2