Memantine for Agitation in Dementia
NCT00371059 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 153
Last updated 2022-04-06
Summary
We plan to evaluate the use of memantine in Alzheimer's disease to control agitation in the acute situation i.e under 12 weeks
Conditions
Interventions
- DRUG
-
Memantine
Memantine 10mg BD
- DRUG
-
Placebo 10 mgs BD
Sponsors & Collaborators
-
University of Oxford
collaborator OTHER -
Institute of Psychiatry, London
collaborator OTHER -
University of London
collaborator OTHER -
University College, London
collaborator OTHER -
Indiana University School of Medicine
collaborator OTHER -
East Kent Hospitals University NHS Foundation Trust
lead OTHER_GOV
Principal Investigators
-
CHRIS FOX, MBBSBscMSC · KENT AND MEDWAY NHS AND SOCIAL CARE PARTNERSHIP TRUST
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-09-30
- Primary Completion
- 2009-06-30
- Completion
- 2009-09-30
Countries
- United Kingdom
Study Locations
More Related Trials
-
Effect of Memantine on Functional Communication in Patients With Alzheimer's Disease
NCT00469456 ·Status: COMPLETED ·Phase: PHASE4
-
Memantine for Agitation and Aggression in Severe Alzheimer's Disease
NCT00401167 ·Status: COMPLETED ·Phase: PHASE4
-
The Use of Memantine for Prevention of Alzheimer's Disease
NCT05063851 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Memantine on Aggression and Agitation of Alzheimer's Disease (AD)
NCT00703430 ·Status: UNKNOWN ·Phase: NA
-
Biomarker Predictors of Memantine Sensitivity in Patients With Alzheimer's Disease
NCT03703856 ·Status: COMPLETED ·Phase: PHASE4
-
The Effect of Memantine on Brain Structure and Chemistry in Alzheimer's Disease Patients
NCT00255086 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of MP-101 in Dementia-Related Psychosis and/or Agitation and Aggression
NCT03044249 ·Status: TERMINATED ·Phase: PHASE2
-
The Efficacy of a Combination Regimen in Patients With Mild to Moderate Probable Alzheimer's Disease
NCT01921972 ·Status: COMPLETED ·Phase: PHASE4
-
Assessing Clinical Outcomes in Alzheimer's Disease Agitation
NCT04797715 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Melatonin: Sleep Problems in Alzheimer's Disease
NCT00000171 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of Memantine in Moderate to Severe Alzheimer's Disease
NCT00857649 ·Status: TERMINATED ·Phase: PHASE3
-
Memantine Hydrochloride for Treatment of Cognitive Dysfunction Due to Traumatic Brain Injury
NCT06337994 ·Status: COMPLETED ·Phase: PHASE3
-
A Study Of PF-04447943 Compared To Placebo In Subjects With Mild To Moderate Alzheimer's Disease
NCT00930059 ·Status: COMPLETED ·Phase: PHASE2
-
Memantine (10mg BID) for the Frontal and Temporal Subtypes of Frontotemporal Dementia
NCT00545974 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Evaluate the Effects of NMRA-323511 Among Healthy Elderly and Adults With Agitation Associated With Dementia Due to Alzheimer's Disease
NCT06546995 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of Memantine Versus Placebo on Ischemic Stroke Outcome
NCT02535611 ·Status: COMPLETED ·Phase: PHASE3
-
ITI-007 for the Treatment of Agitation in Patients With Dementia, Including Alzheimer's Disease
NCT02817906 ·Status: TERMINATED ·Phase: PHASE3
-
A Clinical Study Evaluating the Effects of Memantine on Brain Atrophy in Patients With Alzheimer's Disease
NCT00862940 ·Status: COMPLETED ·Phase: PHASE4
-
Valproate in Dementia (VALID)
NCT00071721 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of Galantamine in the Treatment of Alzheimer's Disease
NCT00000172 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's
NCT00105547 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of Memantine on Magnetic Resonance (MR) Spectroscopy in Subjects at Risk for Alzheimer's Disease
NCT00933608 ·Status: COMPLETED ·Phase: PHASE4
-
Delaying the Progression of Driving Impairment in Individuals With Mild Alzheimer's Disease
NCT00476008 ·Status: COMPLETED ·Phase: PHASE4
-
Prediction of Cognitive Properties of Memantine for Neurodegenerative Diseases
NCT02288000 ·Status: TERMINATED ·Phase: PHASE1
-
Effect of Memantine on Cognitive Impairment in Patients With Epilepsy
NCT04417543 ·Status: COMPLETED ·Phase: PHASE1