Efficacy Study of Memantine Hydrochloride and Escitalopram for the Treatment of Co-Morbid Depression and Alcoholism.
NCT00368862 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2006-08-29
Summary
The aim of the present study was to examine the influence of memantine, a noncompetitive NMDA receptor blocker, in depression co-morbid with long term alcohol heavy use comparing to SSRI-inhibitor, escitalopram. Second goal is to compare their influence to cognitive tasks and the third goal is to follow up alcohol-use with these two medicines.
Conditions
- Alcoholism
- Depression
Interventions
- DRUG
-
Ebixa (memantine hydrochloride)
- DRUG
-
Cipralex (escitalopram)
Sponsors & Collaborators
-
Finnish Foundation for Alcohol Studies
collaborator OTHER -
Finnish Institute for Health and Welfare
lead OTHER_GOV
Principal Investigators
-
Hannu E Alho, MD, PhD · National Public Health Institute, Department of Mental health and Alcohol Research
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 25 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2005-12-31
- Completion
- 2006-06-30
Countries
- Finland
Study Locations
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