Evaluation of Bacteria in the Mouth and Throat of Healthy Adults Before and After the Administration of Either Levofloxacin or Azithromycin, Both Antibiotic Medications
NCT00821782 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 143
Last updated 2011-05-19
Summary
Evaluation of bacteria in the mouth and throat before study drug ( Levofloxacin, floroquinolone antibiotic and Azithromycin, a macrolide antibiotic) is started and then periodically for 6 weeks after the last dose of study drug is taken
Conditions
- Healthy Volunteer
Interventions
- DRUG
-
Levofloxacin; Azithromycin
Sponsors & Collaborators
-
Ortho-McNeil Janssen Scientific Affairs, LLC
lead INDUSTRY
Principal Investigators
-
Ortho-McNeil Janssen Scientific Affairs, LLC Clinical Trial · Ortho-McNeil Janssen Scientific Affairs, LLC
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2006-06-30
- Completion
- 2006-09-30
More Related Trials
-
A Study of the Effectiveness and Safety of High Dose, Short-course Levofloxacin in the Treatment of Acute Bacterial Exacerbation (Worsening) of Chronic Bronchitis.
NCT00042718 ·Status: COMPLETED ·Phase: PHASE3
-
Beta-lactam Plus Levofloxacin to Enhance Therapy in Streptococcal Septicemia
NCT07240077 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
A Study Evaluating the Safety and Efficacy of Treating Sinus Infection With Levofloxacin 750 mg for 5 Days.
NCT00236652 ·Status: COMPLETED ·Phase: PHASE3
-
A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Acute Symptoms of Chronic Bronchitis
NCT00644449 ·Status: COMPLETED ·Phase: PHASE3
-
An Open, Prospective, Randomized, Multicenter Study of the Efficacy and Safety of Intravenous Followed by Oral Azithromycin Versus Cefuroxime Alone or With Oral Erythromycin for the Treatment of Chinese Patients Who Were Hospitalized for Pneumonia
NCT00648726 ·Status: COMPLETED ·Phase: PHASE3
-
A Multicenter, Randomized, Double-Blind, Double-Dummy Comparative Trial of Azithromycin Sustained Release Versus 3-Day Azithromycin for the Treatment of Strep Throat in Adolescents and Adults
NCT00644293 ·Status: COMPLETED ·Phase: PHASE3
-
A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Sinus Infections in Adults
NCT00643409 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Cefuroxime Axetil in the Treatment of Adults With Persistent Bronchitis Experiencing Rapid Onset of Severe Worsening of Symptoms Caused by Bacteria
NCT00269932 ·Status: COMPLETED ·Phase: PHASE3
-
Levofloxacin in Bacterial Rhinosinussitis
NCT02712502 ·Status: COMPLETED
-
LOAD VS Levofloxacine Concomitant
NCT04626193 ·Status: UNKNOWN ·Phase: PHASE4
-
Efficacy and Safety Study of Oral CEM-101 Compared to Oral Levofloxacin in Treatment of Patients With Community-Acquired Bacterial Pneumonia
NCT01168713 ·Status: COMPLETED ·Phase: PHASE2
-
Outpatient Registry Trial of Respiratory Tract Infections in Adults
NCT00245453 ·Status: WITHDRAWN ·Phase: PHASE4
-
Special Investigation Of Azithromycin IV For Legionnaires' Disease (Regulatory Post Marketing Commitment Plan)
NCT01784770 ·Status: COMPLETED
-
Multiple Oral Dose Safety, Tolerability And Pharmacokinetic Study Of PF-04287881 In Healthy Adult Subjects
NCT01026545 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of the Safety and Effectiveness of Levofloxacin Compared With Amoxicillin/Clavulanate Potassium in the Treatment of Adults With Rapid Onset of Severe Inflammation/Infection of the Sinuses
NCT00249210 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of the Safety and Effectiveness of Levofloxacin Compared With Lomefloxacin in the Treatment of Complicated Urinary Tract Infections
NCT00258102 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of the Effectiness and Safety of Levofloxacin in Treating Children With a Rapid and Severe Onset of Infection and Inflammation of the Middle Ear That is Difficult to Treat
NCT00044473 ·Status: COMPLETED ·Phase: PHASE3
-
Trimethoprim-Sulfamethoxazole vs Levofloxacin as Targeted Therapy for Stenotrophomonas Maltophilia Infections: a Retrospective Cohort Study
NCT04639817 ·Status: COMPLETED
-
A Multicentre, Randomised, Open-Label Study To Compare The Efficacy And Safety Of Azithromycin For 5 Days With Those Of Amoxicillin-Clavulanic Acid In Patients With Chronic Bronchitis
NCT00649831 ·Status: COMPLETED ·Phase: PHASE3
-
Comparative Effects of Azithromycin, Telithromycin and Levofloxacin on Drug Metabolizing Enzymes
NCT00164112 ·Status: COMPLETED ·Phase: PHASE4
-
Non-Interventional Open Label Prospective Comparative Observational Study Of Evaluation Of Compliance In The Empiric Treatment With Azithromycin SR Versus Amoxiclav 1000 Mg In Adult Patients With Of Acute Bacterial Maxillary Sinusitis
NCT01032174 ·Status: COMPLETED
-
Macrolide Mediates Pulmonary Infection of Pseudomonas Aeruginosa
NCT02491723 ·Status: COMPLETED ·Phase: NA
-
Study Comparing the Clinical Efficacy and Health Outcomes of Outpatients With Mild to Moderate Community-Acquired Pneumonia (CAP) Treated With Either Telithromycin Once Daily for 7 Days, or Azithromycin Once Daily for 5 Days
NCT00237445 ·Status: TERMINATED ·Phase: PHASE4
-
A Relative Bioavailability Study of 200mg/5 mL Azithromycin Oral Suspension Under Non-Fasting Conditions
NCT00830336 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Measure the Impact of Antibiotics on Bacterial Flora in Adults With Acute Sinusitis
NCT00245440 ·Status: TERMINATED ·Phase: PHASE4