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Cognitive Therapy for Negative Symptoms and Functioning

NCT00350883 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 61

Last updated 2012-05-03

No results posted yet for this study

Summary

This clinical trial tests the effectiveness of cognitive therapy (CT) to improve outcomes in outpatients diagnosed with schizophrenia or schizoaffective disorder who manifest prominent negative symptoms. It is hypothesized that patients receiving cognitive therapy will manifest lower negative symptom levels and improved engagement in constructive activity relative to patients who receive treatment-as-usual. Further, it is predicted that these differences between CT and TAU will be larger when patients are assessed 6 and 12 months after the end of treatment (18 and 24 months after study entry).

Conditions

Interventions

BEHAVIORAL

Cognitive Therapy

Goal-oriented talk therapy

OTHER

Treatment as Usual

Keep getting usual care

Sponsors & Collaborators

Principal Investigators

  • Aaron T Beck, MD · University Professor, Department of Psychiatry, University of Pennsylvania

  • Paul M Grant, PhD · Assistant Professor, Department of Psychiatry, University of Pennsylvania

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-07-31
Primary Completion
2011-11-30
Completion
2011-11-30

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00350883 on ClinicalTrials.gov