Emotion and Motivation in Patients With Psychosis

NCT02853019 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 41

Last updated 2025-08-19

No results posted yet for this study

Summary

Anhedonia and avolition reflect emotional and motivational disorders, respectively. However, if these disorders play a major role in the symptomatology of schizophrenia, their mechanisms remain poorly understood, and existing treatments are inefficient on these symptoms. The literature suggests that the impairment does not concern emotion or motivation per se, but rather their influence on cognition. This project aims at using recent advances in the fundamental domain to better understand the cognitive and neuronal mechanisms of the patients' alterations, and especially how emotion and motivation influence cognition in schizophrenia.

Conditions

Interventions

OTHER

Electroencephalogram

electrophysiological measurements (evoked potentials) based on neural activity when visualizing stimuli

BEHAVIORAL

Cognitive tasks

\- clinical scales and subjective assessments of emotional and motivational stimuli

BEHAVIORAL

subjective evaluation scales

\- clinical scales and subjective assessments of emotional and motivational stimuli

Sponsors & Collaborators

  • Institut National de la Santé Et de la Recherche Médicale, France

    collaborator OTHER_GOV
  • University Hospital, Strasbourg, France

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-02-02
Primary Completion
2025-06-01
Completion
2025-06-01

Countries

  • France

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02853019 on ClinicalTrials.gov