Cytogenetic Study of Ocular Melanoma
NCT00344799 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 95
Last updated 2021-03-29
Summary
Patients who are diagnosed with choroidal melanoma and undergo I-125 plaque or enucleation surgery consent to participate in the study. A tumor sample taken during surgery is studied in the lab for genetic features. These features and features of subjects' clinical course are recorded. Analysis of the data may identify genetic features that are indicative of prognostic factors including risk of metastasis.
Conditions
- Choroidal Melanoma
Sponsors & Collaborators
-
Jonsson Comprehensive Cancer Center
lead OTHER
Principal Investigators
-
Tara M McCannel, MD, PhD · Jules Stein Eye Institute, UCLA
-
Bradley R Straatsma, MD, JD · Jules Stein Eye Institute, UCLA
-
Lynn Gordon, MD, PhD · Jules Stein Eye Institute, UCLA
-
Ben Glasgow, MD · Jules Stein Eye Institute, UCLA
-
Nagesh P Rao, PhD · UCLA Pathology and Laboratory Medicine
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-01-08
- Primary Completion
- 2020-10-23
- Completion
- 2020-10-23
Countries
- United States
Study Locations
More Related Trials
-
S0334 Analyzing Chromosomes in Patients With Newly Diagnosed Multiple Myeloma or Other Blood Disease
NCT00898066 ·Status: COMPLETED
-
Study of Circulating Tumoral DNA in Metastatic Choroidal Melanoma
NCT01334008 ·Status: COMPLETED ·Phase: NA
-
Analysis of Molecular Biomarkers in Periocular Adnexal Tumours
NCT06080009 ·Status: RECRUITING ·Phase: NA
-
Study Investigating MEN1 and SDHD in Familial Carcinoid Tumors
NCT00672269 ·Status: UNKNOWN
-
Genetic Mutations and Environmental Exposure in Young Patients With Retinoblastoma and in Their Parents and Young Healthy Unrelated Volunteers
NCT00690469 ·Status: COMPLETED
-
Sentinel Lymph Node (SLN) Biopsy for Conjunctival/Eyelid Melanoma
NCT00386906 ·Status: COMPLETED ·Phase: PHASE1
-
Biomarkers in Predicting Response to Chemotherapy in Patients With Advanced or Metastatic Melanoma Previously Treated With Carboplatin and Paclitaxel With or Without Sorafenib Tosylate
NCT01209299 ·Status: COMPLETED
-
Validation of a Molecular Prognostic Test for Eye Melanoma
NCT00406120 ·Status: WITHDRAWN
-
Studying Biomarkers in Samples From Younger Patients With Malignant Germ Cell Tumor Progression
NCT01433224 ·Status: COMPLETED
-
S9431: Studying Genes and Immune Response in Tumor Samples From Patients With Locally Advanced or Metastatic Melanoma
NCT00898183 ·Status: COMPLETED
-
Understanding the Transition from Normal Melanocytes to Nevus to Melanoma
NCT06605417 ·Status: RECRUITING
-
Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study
NCT03707574 ·Status: COMPLETED
-
Perioperative Examination of Inflammatory Markers in Relation to Sentinel Lymph Node Biopsy in Patients With Melanoma; a Pilot Study
NCT05817149 ·Status: COMPLETED
-
DNA Repair, p53 and Apoptosis Phenotypes in Lung Cancer
NCT00339859 ·Status: COMPLETED
-
Biomarkers in Predicting Response to Chemotherapy in Samples From Young Patients With Osteosarcoma
NCT01374672 ·Status: COMPLETED
-
Studying Tumor Tissue Samples From Patients With Melanoma Who Have Undergone Sentinel Lymph Node Biopsy
NCT00897481 ·Status: UNKNOWN
-
A Prospective Natural History Study in Uveal Melanoma
NCT04588662 ·Status: ACTIVE_NOT_RECRUITING
-
Biology Studies of Hematologic Cancers
NCT00923442 ·Status: ENROLLING_BY_INVITATION
-
Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies
NCT01109394 ·Status: RECRUITING
-
Melanoma Detection by Oblique-Incidence Optical Spectroscopy
NCT00526032 ·Status: COMPLETED
-
Detailed Phenotypic and Genotype Study to Correlate RB1 Mutations Relating to Primary Ocular Tumors and Secondary Extra-ocular Metastasis.
NCT06725173 ·Status: RECRUITING
-
A Storage Facility for Tissues Obtained From Patients With Malignant Melanoma
NCT04567706 ·Status: RECRUITING
-
Melanoma: Genomic Profiles, Molecular Markers and Therapeutic Implications
NCT05119829 ·Status: UNKNOWN
-
Leveraging ctDNA Analysis to Improve Early Detection of Cancer Recurrence in the High-Risk Melanoma Setting
NCT05079113 ·Status: COMPLETED
-
S8600-S9031-S9333-A, Study of DNA in Samples From Patients With Acute Myeloid Leukemia
NCT01434329 ·Status: COMPLETED