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Validation in Humans of Genes Involved in Alcohol Drinking, Stress-Induced Alcohol Drinking and Relapse

NCT00326742 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 281

Last updated 2007-05-10

No results posted yet for this study

Summary

Aim of the project is to validate and functionally characterize the combined impact of candidate genes and stress exposure on drinking in adolescents. Lifetime and recent stress experiences and drinking are recorded in a sample of healthy young adults who are genotyped for polymorphisms in candidate genes related to alcoholism. All participants undergo a standard laboratory psychosocial stress test. Our hypothesis is that specific genes can be identified which influence drinking by modulating stress response.

Conditions

  • Alcohol Drinking

Interventions

BEHAVIORAL

Trier Social Stress Test

Sponsors & Collaborators

  • German Federal Ministry of Education and Research

    collaborator OTHER_GOV

  • Central Institute of Mental Health, Mannheim

    lead OTHER

Principal Investigators

  • Karl F Mann, Prof · Central Institute of Mental Health, Mannheim

Eligibility

Min Age
18 Years
Max Age
19 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-07-31
Completion
2007-03-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00326742 on ClinicalTrials.gov